Limbitrol
(chlordiazepoxide / amitriptyline)
Treats anxiety and depression.
Our bottom line
While Limbitrol (chlordiazepoxide / amitriptyline) as a combination can be used to treat both anxiety and depression, other medicines are considered first choice because chlordiazepoxide can be potentially addicting.
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (chlordiazepoxide / amitriptyline)
Upsides
- Limbitrol (chlordiazepoxide / amitriptyline) is available as a generic.
- Limbitrol (chlordiazepoxide / amitriptyline) works faster than amitriptyline alone.
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What to expect from chlordiazepoxide / amitriptyline, on one page
Download Fact SheetDownsides
- Limbitrol (chlordiazepoxide / amitriptyline) is only available in certain strengths, so it can be difficult to customize a dose that treats both anxiety and depression.
- Limbitrol (chlordiazepoxide / amitriptyline) contains chlordiazepoxide, which can be potentially addicting.
- You might not notice any changes in your mood until you've been taking Limbitrol (chlordiazepoxide / amitriptyline) for several weeks.
- Amitriptyline alone is considered a better treatment for anxiety and depression than Limbitrol (chlordiazepoxide / amitriptyline).
- Other medicines are considered first choice for treating anxiety and depression over Limbitrol (chlordiazepoxide / amitriptyline).
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What to expect from chlordiazepoxide / amitriptyline, on one page
Download Fact SheetLimbitrol (chlordiazepoxide / amitriptyline) is a combination of 2 medicines. Chlordiazepoxide is a benzodiazepine, and it calms activity in a part of the brain responsible for emotional responses. Amitriptyline is a tricyclic antidepressant, and it raises the amount of norepinephrine and serotonin in the brain, which can improve mood.
- Drug class: Neuro/psych
- Rx status: Prescription only
- Generic status: Lower-cost generic available (chlordiazepoxide / amitriptyline)
Used for
- Anxiety and depression
Dosage forms
- Pill
Prices and coupons
Skip prices section. Skip to what to expect section.- Rite AidGet free coupon$35.44
- CostcoGet free coupon$45.43
What to expect when you take Limbitrol (chlordiazepoxide / amitriptyline) for Anxiety & depression
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Vision changes
- Drowsiness
- Dry mouth
- Constipation
- Dizziness
- Bloating
Side effect rates for Limbitrol (chlordiazepoxide / amitriptyline)
Risks and Warnings for Limbitrol (chlordiazepoxide / amitriptyline)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › People under age 24
Taking Limbitrol (chlordiazepoxide / amitriptyline) can make you more likely to harm yourself or commit suicide, especially if you are younger and during the first few weeks of taking the medicine. If you or your child feel like they want to hurt themselves while taking Limbitrol (chlordiazepoxide / amitriptyline), call the doctor right away.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Limbitrol (chlordiazepoxide / amitriptyline)
Final section. Do you want to return to drug navigation?Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.
Tip: Always talk with your doctor before you take any medication while pregnant.- Don't drink alcohol or take narcotics, tranquilizers, or antihistamines if you're taking Limbitrol (chlordiazepoxide / amitriptyline). This can slow down your breathing. Talk to your doctor if this is a problem.
- Don't drink alcohol or take any narcotics while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can slow your breathing.
- Limbitrol (chlordiazepoxide / amitriptyline) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how it affects you. This can be worse if you drink alcohol or take narcotics.