Cimzia

(certolizumab)

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Calms the immune system and prevents joint damage.

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Our bottom line

Cimzia (certolizumab) effectively calms down your immune system, but you have to be comfortable receiving injections.

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    $4024.56
Quick facts about Cimzia
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • People taking Cimzia (certolizumab) for Crohn's disease, rheumatoid arthritis and other autoimmune conditions had greater clinical response compared to people who did not take Cimzia (certolizumab).
  • Compared to some other drugs used to treat autoimmune conditions, Cimzia (certolizumab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • You can give yourself Cimzia (certolizumab) on your own at home rather than visiting a clinic or hospital.
  • After the initial dosing, you need to take Cimzia (certolizumab) every 4 weeks.
  • Cimzia (certolizumab) has been on the market for almost 10 years.
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What to expect from Cimzia, on one page

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Downsides

  • Cimzia (certolizumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, or had tuberculosis (TB) in the past.
  • Can in some cases cause bladder infections, rash and respiratory infections (cold or flu)
  • In rare cases, Cimzia (certolizumab) has been associated with cancers in children and adolescents.
  • Can increase your risk of side effects if you have a history of heart failure, nervous system conditions, or hepatitis B.
  • There's no generic available and it can be expensive.
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What to expect from Cimzia, on one page

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How it works

Cimzia (certolizumab) blocks a protein called TNF (tumor necrosis factor) that causes inflammation.

Quick facts about Cimzia
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Injection
Tried Cimzia? Write a review!

Prices and coupons

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What to expect when you take Cimzia (certolizumab) for Autoimmune diseases

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Allergic reaction
  • Infections
  • Injection site reactions
  • Upper airway infection
  • High blood pressure
  • Joint pain
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Side effect rates for Cimzia (certolizumab)

From 1234 clinical trials of Cimzia when taken for crohn's disease (400 mg)
  • Infections
    38%38%
    30%30%
  • Upper airway infections
    20%20%
    13%13%
  • Urinary tract infections
    7%7%
    6%6%
  • Joint pain
    6%6%
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Cimzia.

Cimzia (certolizumab)
Placebo

People taking Cimzia felt side effect more

People taking Cimzia felt side effect less

No difference

Risks and Warnings for Cimzia (certolizumab)

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    • Higher risk if:
    • Taking other immunosuppressant medications such as methotrexate or steroids
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities

    Cimzia (certolizumab) can increase your risk of serious or life-threatening infections. In some cases, existing inactive infections can be reactivated such as tuberculosis (TB) or hepatitis B virus (HBV). You may need to take medicine for TB before you can begin taking Cimzia (certolizumab). If you develop symptoms of cough, fever, chills, muscle aches, fatigue, dark urine, yellowing of skin/eyes, loss of appetite, vomiting, change in stool color, stomach discomfort, or skin rash, tell your doctor right away. Live vaccines are not recommended while taking Cimzia (certolizumab) - talk to your doctor before receiving any vaccines.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Cimzia (certolizumab)

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Kidneys and liver
  • Worth it
    Low hassle
    Reviewed Cimziaon 2/22/2017Has to be delivered to your home. I am having trouble finding a Medicare part D formulary in NC that carries it.
    64
    Woman
    Rheumatoid arthritis (moderate to severe)
Pain
  • Worth it
    Low hassle
    Reviewed Cimziaon 9/24/2016Let it get to room temp before injecting it, seems to hurt less.
    37
    Woman
    Rheumatoid arthritis (moderate to severe)