Clozaril

(clozapine)

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Helps control your thoughts and actions.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Clozaril (clozapine) treats schizophrenia when other drugs haven't worked, but you'll have to get regular blood work done because it can have very serious side effects.

Lowest price near you
  • Lowest price with coupon
    $774.00
Quick facts about Clozaril
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (clozapine)

Upsides

  • Studies show that Clozaril (clozapine) effectively treats schizophrenia when other medications have failed. Clozaril (clozapine) also reduces risk of suicidal behavior.
  • Has the lowest risk of causing movement problems when compared to other antipsychotic medicines.
  • Clozaril (clozapine) is available as a normal tablet and as a mint-flavored tablet that dissolves on the tongue without water.
  • Safer than other similar medicines during pregnancy.
  • Available as a generic, which is cheaper.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Clozaril, on one page

Download Fact Sheet
Tried Clozaril? Write a review!

Downsides

  • You need to get blood work done every time you get a prescription filled for Clozaril (clozapine). Once it is ready at the pharmacy, you need to pick it up within 7 days.
  • You can only get Clozaril (clozapine) at certain pharmacies that are registered to provide it.
  • You need to limit the amount of alcohol you drink while taking Clozaril (clozapine).
  • Clozaril (clozapine) can cause high blood sugar, high cholesterol, and weight gain.
  • May not be optimal for someone with a history of seizures.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Clozaril, on one page

Download Fact Sheet
How it works

Clozaril (clozapine) is an atypical antipsychotic. It changes dopamine and serotonin activity in your brain, which affect thoughts and mood.

Quick facts about Clozaril
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (clozapine)

Used for

  • Schizophrenia
  • Suicidal behavior in schizophrenia
  • Psychosis in Parkinson's disease

Dosage forms

  • Pill
  • Dissolving tablet
  • Liquid
Tried Clozaril? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 1 (100ml-of-50mg-ml) bottle-of-oral-suspension of clozapine near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take Clozaril (clozapine) for Schizophrenia

Skip what to expect section. Skip to side effects section.
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Drowsiness/sedation
  • Dizziness/vertigo
  • Headache
  • Fast heartbeat
  • Constipation
  • Salivation
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Clozaril (clozapine)

From 842 clinical trials of Clozaril when taken for schizophrenia
  • Drowsiness/sedation
    39%39%
  • Salivation
    31%31%
  • Fast heartbeat
    25%25%
  • Dizziness/vertigo
    19%19%
  • Constipation
    14%14%
  • Low blood pressure
    9%9%
  • Headache
    7%7%
  • Tremor
    6%6%
  • Fainting
    6%6%
  • Sweating
    6%6%
  • Dry mouth
    6%6%
  • Nausea
    5%5%
  • Vision problems
    5%5%
  • Fever
    5%5%
  • Disturbed sleep/nightmares
    4%4%
  • Restlessness
    4%4%
  • Loss of muscle movement
    4%4%
  • Agitation
    4%4%
  • High blood pressure
    4%4%
  • Stomach discomfort/heartburn
    4%4%
  • Weight gain
    4%4%
  • Seizures (convulsions)
    3%3%
  • Rigidity
    3%3%
  • Restlessness
    3%3%
  • Confusion
    3%3%
  • Nausea/vomiting
    3%3%
  • Low white blood cells
    3%3%
  • Fatigue
    2%2%
  • Trouble sleeping
    2%2%
  • Diarrhea
    2%2%
  • Problems urinating
    2%2%
  • Rash
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Clozaril.

Clozaril (clozapine)
Placebo

People taking Clozaril felt side effect more

People taking Clozaril felt side effect less

No difference

Risks and Warnings for Clozaril (clozapine)

Skip risks section. Skip to common concerns section.
  • Clozaril (clozapine) can cause low white blood cells, which can lead to serious infection and in some cases, death. You'll need to do blood tests before your doctor can refill a prescription for Clozaril (clozapine) to make sure you're not at risk.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Clozaril (clozapine)

Final section. Do you want to return to drug navigation?
Alcohol
  • You need to limit the amount of alcohol you drink while taking Clozaril (clozapine).
Food
  • Take with or without food.
Weight
  • Clozaril (clozapine) can cause high blood sugar or diabetes, high cholesterol, and weight gain. These changes may increase risk of heart disease and stroke. Talk to your doctor about your risks and preventive measures you can take.
  • Can affect your weight, cholesterol, and blood sugar control.
  • Clozaril (clozapine) can cause high blood sugar, high cholesterol, and weight gain.