Colcrys

(colchicine)

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Prevents and treats gout.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Colcrys (colchicine) is a second-choice treatment for gout attacks. Be careful how much you use since it can cause problems with your blood.

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  • Price before coupon
    $218.80
  • Lowest price with coupon
    $123.10
  • Savings
    44%
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Quick facts about Colcrys
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (colchicine)

Upsides

  • Colcrys (colchicine) treats and stops sudden gout attacks.
  • It can be used to prevent gout when people are first starting on allopurinol.
  • Colcrys (colchicine) also treats Familial Mediterranean fever.
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What to expect from Colcrys, on one page

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Downsides

  • Colcrys (colchicine) doesn't work as well as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids to treat gout attacks.
  • Taking Colcrys (colchicine) for too long can cause problems with your blood.
  • Doses needs to be changed if you have kidney or liver problems.
  • While Colcrys (colchicine) stops the redness and swelling of gout attacks, it doesn't stop the pain.
  • If you're taking Colcrys (colchicine) to stop gout flare-ups, you can only use it for 3 to 6 months after your levels have stabilized.
  • The capsules (Mitigare) are only approved for prevention, but not treatment of gout.
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What to expect from Colcrys, on one page

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How it works

Colcrys (colchicine) stops the redness and swelling in gout attacks by blocking the cells that cause inflammation from going to the affected joints.

Quick facts about Colcrys
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (colchicine)

Used for

Dosage forms

  • Pill
Tried Colcrys? Write a review!

Prices and coupons

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What to expect when you take Colcrys (colchicine) for Gout

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Diarrhea
  • Nausea
  • Stomach upset
  • Muscle pain
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Side effect rates for Colcrys (colchicine)

From 133 clinical trials of Colcrys when taken for gout flare (1.8mg over 1 hour)
  • Stomach problems
    26%26%
    20%20%
  • Diarrhea
    23%23%
    14%14%
  • Nausea
    4%4%
    5%5%
  • Gout
    4%4%
    2%2%
  • Throat pain
    3%3%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Colcrys.

Colcrys (colchicine)
Placebo

People taking Colcrys felt side effect more

People taking Colcrys felt side effect less

No difference

Risks and Warnings for Colcrys (colchicine)

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  • Colcrys (colchicine) can lower your body's ability to make new blood cells. This can happen even when you're using Colcrys (colchicine) correctly, and can be serious if it's not caught in time. Let your doctor know if you have frequent bleeding, bruising, fevers, or always feel tired.

Pharmacist Q&A

Colcrys (colchicine) questions for

Frequently Asked Questions

This medication treats familial Mediterranean fever (FMF) in adults and children 4 years and older.

Who is this drug for?

This medication treats familial Mediterranean fever (FMF) in adults and children 4 years and older.

Common concerns from people taking Colcrys (colchicine)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Colcrys
CWeigh risks vs. benefits
Interactions
  • Many foods and medicines can interact with Colcrys (colchicine), which can be dangerous. If you have liver or kidney problems, these interactions can be worse. Talk to your doctor and pharmacist to see what dose of Colcrys (colchicine) you should take based on your diet and other medicines.
Food
  • Take Colcrys (colchicine) with or without food.
Kidneys and liver
  • Doses needs to be changed if you have kidney or liver problems.
  • Worth it
    Worked well
    Low hassle
    Reviewed Colcryson 2/10/2021Was prescribed colchicine to treat pseudo-gout, caused by calcium phosphate crystals. Prescribed a very small dose, one .5 mg tablet per day, due to kidney disease. Worked extremely well to prevent occurrence of pseudo-gout attacks on feet, ankles and knees. Replaced with allopurine for also treating gout.
    71
    Man
    A year or so
    Gout prevention