Compro
(Prochlorperazine)
Helps you feel less queasy.
Our bottom line
Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (prochlorperazine)
Upsides
- Available in generic, so it's cheap.
- Can be taken by mouth, as a shot, or rectally.
- Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
Downsides
- Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
- Can't be used by people over 65 because they can be more affected by the side effects.
- It can make you more likely to get heatstroke.
Compro (Prochlorperazine) is an antiemetic (anti-nausea medicine). It works by blocking signals in the part of your brain that causes vomiting.
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (prochlorperazine)
Dosage forms
- Pill
- Suppository
Prices and coupons
Skip prices section. Skip to what to expect section.- Pay as low as$8.96Retail priceRetail priceLearn more
- Kroger PharmacyGet free coupon$11.76
- Rite AidGet free coupon$12.07
- CostcoGet free coupon$13.65
Side effect rates for Compro (Prochlorperazine)
Manufacturers don’t say how common these side effects are when taking Compro for
- Agranulocytosis
- Amenorrhoea
- Anaemia
- Aplastic anaemia
- Haemolytic anaemia
- Angioedema
- Asphyxia
- Asthma
- Edema cerebral
- Breast feeding
- Catatonia
- Cholestasis
- Constipation
- Convulsion
- Cough
- Sudden death
- Dysphagia
- Dermatitis
- Dermatitis exfoliative
- Dermatitis contact
- Dizziness
- Drooling
- Drowsiness
- Dyspnoea
- Eczema
- Oedema
- Eosinophilia
- Grand mal convulsion
- Petit mal epilepsy
- Body temperature increased
- Glycosuria
- Gynaecomastia
- Headache
- Cardiac arrest
- Blood disorder
- Hyperglycaemia
- Hypersensitivity
- Hypoglycaemia
- Hypotension
- Infection
- Influenza
- Jaundice
- Jaundice cholestatic
- Laryngeal oedema
- Leukopenia
- Systemic lupus erythematosus
- Miosis
- Mitral valve incompetence
- Muscle rigidity
- Mydriasis
- Nasal congestion
- Neuroleptic malignant syndrome
- Pancytopenia
- Ileus paralytic
- Phaeochromocytoma
- Pigmentation
- Priapism
- Pruritus
- Purpura
- Retinal disorder
- Retinitis pigmentosa
- Skin disorder
- Pigmentation skin
- Muscle spasms
- Torticollis
- Tremor
- Trismus
- Erythema
- Urticaria
- Weight increased
- Dry mouth
- Urinary retention
- Oculogyric crisis
- Oedema peripheral
- Cogwheel rigidity
- Electroencephalogram abnormal
- Hepatocellular injury
- Opisthotonus
- Pregnancy test false positive
- Hyperreflexia
- Orofacial dyskinesia
- Menstruation irregular
- Corneal deposits
- Obstipation
- Gait shuffling
- Increased appetite
- Extrapyramidal symptoms
- Tenderness
- Keratopathy
- Galactorrhoea
- Throat tightness
- Pregnancy test positive
- Protrusion tongue
- Erectile dysfunction
- Throat sore
- Colon atonic
- Dependence physiological
- Anaphylactoid reaction
- Vision blurred
- Photosensitivity
- Akathisia
- Hyperpyrexia
- Dystonia
- Lupus erythematosus
- Movements involuntary
- Pseudoparkinsonism
- Tremulousness
- Feeling jittery
- Sedation
- Motor restlessness
- Thrombocytopenic purpura
- Insomnia
- Malignant syndrome NOS
- Ileus
- Death
Risks and Warnings for Compro (Prochlorperazine)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Over age 65
- › Dementia
- › Taking antipsychotics
It is not recommended for people with dementia over age 65 who are taking antipsychotic medications to take Compro (Prochlorperazine), as there is an increased risk of death. Your doctor will discuss alternatives.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Compro (Prochlorperazine)
Final section. Do you want to return to drug navigation?The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.
Tip: Always talk with your doctor before you take any medication while pregnant.- Don't drink alcohol to avoid intense side effects.
- Taking certain medications for pain, allergies, or mood conditions can worsen the side effects of Compro.
- You'll likely feel very sleepy, sluggish, or less alert after taking Compro. Avoid driving or other tasks that require your focused attention; be safe.
- Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.