Creon

(pancrelipase)

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Helps breaks down food.

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Our bottom line

Creon (pancrelipase) works well breaking down food when your pancreas isn't working well, but you'll need to work with your doctor to find a dose that works best for you.

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    $300.38
Quick facts about Creon
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • The sprinkle capsule can be swallowed whole or can be opened up and mixed with applesauce if you have a hard time swallowing pills.
  • It's safe to use for children and infants.
  • Studies show that Creon (pancrelipase) works well to lower stool frequency and improve stomach pain, gassiness, and stool consistency.
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What to expect from Creon, on one page

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Downsides

  • You need to take Creon (pancrelipase) with every meal and snack.
  • It may affect your blood sugar levels so you'll have to check your sugar levels more often if you're diabetic.
  • Sometimes you'll need to take another medication with Creon (pancrelipase) for it to work well.
  • It can be expensive and there is no generic version.
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What to expect from Creon, on one page

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How it works

Creon (pancrelipase) replaces three important enzymes that are normally made in the pancreas to break down food.

Quick facts about Creon
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Pancreatic insufficiency

Dosage forms

  • Pill
  • Delayed-release
Tried Creon? Write a review!

Prices and coupons

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What to expect when you take Creon (pancrelipase) for Pancreatic insufficiency

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Vomiting
  • High blood sugar
  • Stomach pain
  • Abnormal stool
  • Gassy feeling
  • Frequent bowel movements
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Side effect rates for Creon (pancrelipase)

From 96 clinical trials of Creon when taken for pancreatic insufficiency
  • High blood sugar
    8%8%
    7%7%
  • Vomiting
    6%6%
    2%2%
  • Dizziness
    4%4%
    2%2%
  • Cough
    4%4%
  • Low blood sugar
    4%4%
    3%3%
  • Abdominal pain
    4%4%
    3%3%
  • Abnormal feces
    4%4%
  • Gassy
    4%4%
  • Frequent bowel movements
    4%4%
  • Common cold
    4%4%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Creon.

Creon (pancrelipase)
Placebo

People taking Creon felt side effect more

People taking Creon felt side effect less

No difference

Risks and Warnings for Creon (pancrelipase)

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    • Higher risk if:
    • High dose
    • Long-term use

    Creon (pancrelipase) can sometimes cause serious scarring of the colon, especially when used in high doses or for a long time. You should take Creon (pancrelipase) only as directed, and not more than or longer than your doctor recommends.

Common concerns from people taking Creon (pancrelipase)

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Food
  • Creon (pancrelipase) should be taken with every meal and snack.
  • You need to take Creon (pancrelipase) with every meal and snack.