Cubicin

(daptomycin)

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Treats bacterial infections.

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Our bottom line

Cubicin (daptomycin) is an antibiotic that's usually only given in the hospital for serious infections. It can be given at home, but you will have to be taught how to inject it correctly.

Quick facts about daptomycin
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (daptomycin)

Upsides

  • Cubicin (daptomycin) is good at treating severe and complicated bacterial infections.
  • It is able to kill bacteria that have resistance to other antibiotics.
  • Most people who take Cubicin (daptomycin) have few side effects.
  • You usually only need to take it once a day.
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What to expect from daptomycin, on one page

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Downsides

  • Cubicin (daptomycin) is usually only given for extremely serious infections that haven't responded to other antibiotics.
  • Cubicin (daptomycin) can cause muscle aches and weakness, which can lead to kidney problems.
  • You might need to have more blood tests done while taking Cubicin (daptomycin).
  • Like most antibiotics, it is common to have diarrhea when taking this medicine.
  • While Cubicin (daptomycin) is generic, it is usually very expensive.
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What to expect from daptomycin, on one page

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How it works

Cubicin (daptomycin) is an antibacterial. It kills bacteria by preventing them from making their own DNA, RNA, and proteins they need to survive.

Quick facts about daptomycin
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (daptomycin)

Used for

Dosage forms

  • Injection
Tried daptomycin? Write a review!

What to expect when you take Cubicin (daptomycin) for Bacterial infection

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
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  • Possible side effects
  • Allergic reaction
  • Diarrhea
  • Severe diarrhea (C. difficile)
  • Muscle pain
  • Pneumonia
  • Nerve damage
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Side effect rates for Cubicin (daptomycin)

  • Diarrhea
    5%5%
  • Headache
    5%5%
  • Rash
    4%4%
  • Abnormal liver tests
    3%3%
  • Muscle damage
    3%3%
  • Dizziness
    2%2%
  • Urinary tract infection
    2%2%
  • Low blood pressure
    2%2%
  • Shortness of breath
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of daptomycin.

Cubicin (daptomycin)
Placebo

People taking daptomycin felt side effect more

People taking daptomycin felt side effect less

No difference

Risks and Warnings for Cubicin (daptomycin)

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    • Higher risk if:
    • Allergy to antibiotics

    Cubicin (daptomycin) can cause a severe and life-threatening allergic reaction; however, this is rare. Tell your doctor if you have any allergies to antibiotics. If you get a rash, itchy skin, hives, difficulty breathing, or swelling of your face or mouth while taking Cubicin (daptomycin), talk to your doctor or go to the emergency room right away.