Neoral

(cyclosporine)

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Suppresses the immune system.

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Our bottom line

Neoral (cyclosporine) is good at preventing rejection of a transplanted organ, and is also used for treating rheumatoid arthritis and psoriasis.

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Quick facts about cyclosporine
  • Drug class: Transplant
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cyclosporine)

Upsides

  • Neoral (cyclosporine) is safe for pregnant women to use.
  • Neoral (cyclosporine) does not affect blood sugar levels as much as others in the same drug class.
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What to expect from cyclosporine, on one page

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Downsides

  • You'll need regular blood tests to make sure Neoral (cyclosporine) isn't affecting your body negatively.
  • Neoral (cyclosporine) can cause high blood pressure and kidney damage, especially with lifelong use.
  • You might need to take other medications to control your blood pressure while on Neoral (cyclosporine).
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What to expect from cyclosporine, on one page

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How it works

Neoral (cyclosporine) is an immunosuppresant that lowers your immune system activity, so your body doesn't reject a transplanted organ. It also lowers inflammation in the body.

Quick facts about cyclosporine
  • Drug class: Transplant
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cyclosporine)

Used for

  • Prevention of heart transplant rejection
  • Prevention of kidney transplant rejection
  • Prevention of liver transplant rejection

Dosage forms

  • Pill
  • Liquid
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Prices and coupons

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What to expect when you take Neoral (cyclosporine) for Rheumatoid arthritis

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  • First few hoursHours
    First few daysDays
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • High blood pressure
  • Headache
  • Abnormal hair growth
  • Leg cramps/involuntary muscle contractions
  • Burning or tingling in hands, arms, legs, or feet
  • Tremor
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Side effect rates for Neoral (cyclosporine)

From 112 clinical trials of cyclosporine when taken for prevention of heart transplant rejection
  • High blood pressure
    53%53%
  • Abnormal kidney function
    38%38%
  • Tremor
    31%31%
  • Abnormal hair growth
    28%28%
  • Acne
    20%20%
  • Headache
    15%15%
  • Nausea/vomiting
    10%10%
  • Liver damage
    7%7%
  • Stomach discomfort
    7%7%
  • Low white blood cells
    6%6%
  • Blood cell tumor
    6%6%
  • Gum swelling
    5%5%
  • Uncontrolled shaking
    4%4%
  • Diarrhea
    4%4%
  • Swelling of breasts
    4%4%
  • Common cold symptoms
    3%3%
  • Burning or tingling in hands, arms, legs, or feet
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of cyclosporine.

Neoral (cyclosporine)
Placebo

People taking cyclosporine felt side effect more

People taking cyclosporine felt side effect less

No difference

Risks and Warnings for Neoral (cyclosporine)

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    • Higher risk if:
    • › Taking Neoral (cyclosporine) for a long time
    • › Prolonged exposure to sunlight
    • › UV light

    Long-term use of Neoral (cyclosporine) can raise your risk of skin cancer and lymphoma (cancer of the immune system). Limit your exposure to sunlight and check your skin regularly. Let your doctor know right away if you have skin changes, prolonged fevers, unexpected weight loss, extreme tiredness, or lumps in your neck, armpit, or groin.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Neoral (cyclosporine)

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Interactions
  • Neoral (cyclosporine) can interact with many medications and cause serious or life-threatening side effects. Talk to your doctor or pharmacist before starting or stopping medications.
Kidneys and liver
  • Neoral (cyclosporine) can damage your kidneys, especially if you have poor kidney function or are taking other medications that can damage your kidneys. Your doctor will order blood tests and change your dose if needed.
  • Neoral (cyclosporine) can cause high blood pressure and kidney damage, especially with lifelong use.
Weight
  • Neoral (cyclosporine) can raise your risk of serious or life-threatening bacterial, fungal, and viral infections. If you develop symptoms of fever, chills, muscle aches, or you notice dark urine, appetite/weight loss, vomiting, or a skin rash, tell your doctor and get medical care right away.