Pradaxa

(dabigatran)

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Prevents and treats blood clots.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Pradaxa (dabigatran) is an effective oral medicine for preventing and treating blood clots, but it can increase the risk of bleeding especially in older people and those with kidney problems.

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  • Lowest price with coupon
    $387.14
Quick facts about Pradaxa
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Pradaxa (dabigatran) doesn't require regular blood tests or frequent dose changes, unlike Coumadin.
  • Works just as well as other blood thinners in lowering the risk of stroke and heart attacks.
  • In cases of accidental overdose, an antidote is available to reverse the effects of the medicine.
  • May be taken with or without food.
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What to expect from Pradaxa, on one page

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Downsides

  • Pradaxa (dabigatran) is not available in generic form so it can be expensive.
  • Might not be a good option for people age 75 or older and those with kidney problems due to the increased risk of bleeding.
  • Not safe to be used in people with artificial heart valves.
  • Pradaxa (dabigatran) is associated with a higher risk of stomach bleeding compared to Coumadin.
  • Might not be appropriate for people who need to take aspirin or NSAIDs (such as ibuprofen) regularly since it can add to the risk of bleeding.
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What to expect from Pradaxa, on one page

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How it works

Pradaxa (dabigatran) is an anticoagulant that stops blood clots from forming, which helps lower the risks for heart attack and stroke.

Quick facts about Pradaxa
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Pradaxa (dabigatran) for Anticoagulant

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Any bleeding
  • Indigestion
  • Heartburn
  • Stomach pain
  • Stomach bleeding
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Side effect rates for Pradaxa (dabigatran)

From 1343 clinical trials of Pradaxa when taken for treatment and prevention of blood clots (150 mg twice daily)
  • Any bleeding
    11%11%
    6%6%
  • Non-major bleeding
    5%5%
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Pradaxa.

Pradaxa (dabigatran)
Placebo

People taking Pradaxa felt side effect more

People taking Pradaxa felt side effect less

No difference

Risks and Warnings for Pradaxa (dabigatran)

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    • Higher risk if:
    • Stopping Pradaxa (dabigatran) suddenly

    Don't stop taking Pradaxa (dabigatran) suddenly since that can increase your risk for getting life-threatening blood clots or a stroke. Talk to your doctor on any concerns about the medicine.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Pradaxa (dabigatran)

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Price
  • Worth it
    Low hassle
    Reviewed Pradaxaon 12/25/2016the only problem is it's cost.
    58
    Man
    Atrial fibrillation
Food
  • Don't chew, break or open the capsules. Swallow the medicine whole with a full glass of water.
  • Works just as well as other blood thinners in lowering the risk of stroke and heart attacks.
  • May be taken with or without food.
  • Not worth it
    Some hassle
    Reviewed Pradaxaon 10/26/2016Should be taken with food to prevent upset stomach. Also some issue with swallowig capsules. Switching to Eliquis.
    69
    Man
    Atrial fibrillation
  • Worth it
    Low hassle
    Reviewed Pradaxaon 6/23/2015Must take with food and liquid
    78
    Man
    Two years or more
Kidneys and liver
  • Might not be a good option for people age 75 or older and those with kidney problems due to the increased risk of bleeding.
Pain
  • Not worth it
    Some hassle
    Reviewed Pradaxaon 8/23/2017I have a hietal hernia and suffer from pain in the esophagus, but with Pradaxa I had too much trouble controlling the pain. It also caused abdominal upset which didn't let up and I didn't know what to do.
    69
    Woman
    A few months
    Pulmonary embolism prevention