Ampyra

(dalfampridine)

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Improves walking in patients with MS (multiple sclerosis).

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Our bottom line

Ampyra (dalfampridine) is an oral drug for people with difficulty walking due to MS, but may not work for everyone.

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    $2681.57
Quick facts about Ampyra
  • Drug class: autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • There is no other prescription medicine that is proven to improve walking in adults with MS.
  • Ampyra (dalfampridine) can be taken with or without food.
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What to expect from Ampyra, on one page

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Downsides

  • Works well for others, but not at all for some.
  • Expensive since it is brand only and is the only drug that could improve walking if you have MS.
  • Ampyra (dalfampridine) won't slow down or stop multiple sclerosis.
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What to expect from Ampyra, on one page

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How it works

Ampyra (dalfampridine) is believed to enhance conduction of your nerve fibers.

Quick facts about Ampyra
  • Drug class: autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
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Prices and coupons

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What to expect when you take Ampyra (dalfampridine) for Multiple sclerosis

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Urinary tract infection
  • Insomnia
  • Dizziness
  • Headache
  • Nausea
  • Lack of energy
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Side effect rates for Ampyra (dalfampridine)

From 638 clinical trials of Ampyra when taken for multiple sclerosis (10 mg twice daily)
  • Urinary tract infection
    12%12%
    8%8%
  • Insomnia
    9%9%
    4%4%
  • Dizziness
    7%7%
    4%4%
  • Headache
    7%7%
    4%4%
  • Nausea
    7%7%
    3%3%
  • Lack of energy
    7%7%
    4%4%
  • Back pain
    5%5%
    2%2%
  • Balance disorder
    5%5%
    1%1%
  • Multiple sclerosis relapse
    4%4%
    3%3%
  • Tingling or numbness sensation
    4%4%
    3%3%
  • Common cold
    4%4%
    2%2%
  • Constipation
    3%3%
    2%2%
  • Indigestion
    2%2%
    1%1%
  • Throat pain
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Ampyra.

Ampyra (dalfampridine)
Placebo

People taking Ampyra felt side effect more

People taking Ampyra felt side effect less

No difference

Risks and Warnings for Ampyra (dalfampridine)

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    • Higher risk if:
    • History of seizures

    Ampyra (dalfampridine) can cause seizures even in people with no history of seizures. Seizures can happen within days to weeks after starting Ampyra (dalfampridine). Those with a history of seizures should not take Ampyra (dalfampridine). Go to the emergency room and talk to your doctor right away if you do have a seizure.

Common concerns from people taking Ampyra (dalfampridine)

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Kidneys and liver
  • Ampyra (dalfampridine) is removed from your body via your kidneys. If your kidneys don't work well, more Ampyra (dalfampridine) can stay in your body and cause seizures or other serious side effects. You might not be able to take Ampyra (dalfampridine). Talk to your doctor if you have questions