Enablex

(darifenacin)

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Treats overactive bladder.

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Our bottom line

Enablex (darifenacin) is a good treatment for overactive bladder if exercises and other methods haven't worked.

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Quick facts about Enablex
  • Drug class: Renal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (darifenacin)

Upsides

  • Enablex (darifenacin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
  • The tablet is available as a generic.
  • Enablex (darifenacin) is only taken once a day.
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Downsides

  • Enablex (darifenacin) is only recommended after doing exercises, bladder training and changes to your lifestyle haven't helped.
  • Enablex (darifenacin) can cause drowsiness and dizziness and can increase your risk for falls.
  • Enablex (darifenacin) can cause severe dry mouth and eyes and constipation.
  • Generally not recommended if you are 65 or older.
  • Do not use if you have uncontrolled narrow-angle glaucoma.
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What to expect from Enablex, on one page

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How it works

Enablex (darifenacin) is an antimuscarinic. It helps people control the urge to urinate by relaxing the bladder muscles and stopping them from spasming.

Quick facts about Enablex
  • Drug class: Renal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (darifenacin)

Used for

Dosage forms

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Prices and coupons

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What to expect when you take Enablex (darifenacin) for Overactive bladder

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Constipation
  • Dry mouth
  • Dizziness
  • Sleepiness
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Side effect rates for Enablex (darifenacin)

From 722 clinical trials of Enablex when taken for overactive bladder (15 mg)
  • Dry mouth
    35%35%
    8%8%
  • Constipation
    21%21%
    6%6%
  • Indigestion
    8%8%
    3%3%
  • Urinary tract infection
    5%5%
    3%3%
  • Stomach pain
    4%4%
    1%1%
  • Weakness
    3%3%
    1%1%
  • Nausea
    2%2%
    2%2%
  • Dizziness
    2%2%
    1%1%
  • Dry eyes
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Enablex.

Enablex (darifenacin)
Placebo

People taking Enablex felt side effect more

People taking Enablex felt side effect less

No difference

Risks and Warnings for Enablex (darifenacin)

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  • Enablex (darifenacin) rarely can cause swelling in the face, lips, tongue and throat. This can be very dangerous since it can stop your breathing. Go to the emergency room right away if this happens.

Common concerns from people taking Enablex (darifenacin)

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Alcohol
  • Drinks with caffeine, alcohol or carbonation can make your symptoms worse.
Kidneys and liver
  • If you have liver problems, talk to your doctor before starting Enablex (darifenacin). You might have to use a lower dose, or you might not be able to take Enablex (darifenacin) at all.
Sleep
  • You can get drowsy or dizzy on Enablex (darifenacin). Do not stand or sit up too quickly if you’ve been sitting or lying down for a while.
  • Enablex (darifenacin) can cause drowsiness and dizziness and can increase your risk for falls.