Depo-SubQ Provera 104
(Medroxyprogesterone injection)
Prevents pregnancy and relieves symptoms of endometriosis.
Our bottom line
Depo-SubQ Provera 104 (Medroxyprogesterone injection), given every 3 months, effectively prevents pregnancy and relieves pain from endometriosis.
- Drug class: Women's health
- Rx status: Prescription only
- Generic status: No lower cost generic available
Upsides
- One of the most effective methods of preventing pregnancy.
- More effective than some other medicines for treating pain from endometriosis.
- Only given every 3 months.
- Can be used if you're nursing.
- Very few side effects.
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What to expect from Depo-SubQ Provera 104, on one page
Download Fact SheetDownsides
- Requires injection with a needle, which can be difficult for some people.
- Brand name only, so can be costly.
- After 2 years of using Depo-SubQ Provera 104 (Medroxyprogesterone injection), your bones can weaken and be at a higher risk for a fracture.
- Doesn't protect against HIV or other sexually transmitted infections.
- Can't be used in people with liver problems or that who have had breast cancer.
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What to expect from Depo-SubQ Provera 104, on one page
Download Fact SheetDepo-SubQ Provera 104 (Medroxyprogesterone injection) contains a type of hormone known as a progestin. It prevents pregnancy by stopping ovulation, thinning the lining of your uterus, and making it more difficult for sperm to enter the uterus. It also helps relieve pain from endometriosis by thinning the lining of your uterus.
- Drug class: Women's health
- Rx status: Prescription only
- Generic status: No lower cost generic available
Used for
- Birth control
- Endometriosis relief
Dosage forms
- Injection
What to expect when you take Depo-SubQ Provera 104 (Medroxyprogesterone injection) for Birth control
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Headache
- Spotting/breakthrough bleeding
- Weight gain
- Missed period
- Skin irritation where injected
Side effect rates for Depo-SubQ Provera 104 (Medroxyprogesterone injection)
- Headache9%9%
- Spotting/breakthrough bleeding7%7%
- Weight gain6%6%
- Missed period6%6%
- Skin irritation where injected5%5%
The placebo bar shows how common a side effect was for people taking a sugar pill instead of Depo-SubQ Provera 104.
People taking Depo-SubQ Provera 104 felt side effect more
People taking Depo-SubQ Provera 104 felt side effect less
Risks and Warnings for Depo-SubQ Provera 104 (Medroxyprogesterone injection)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Using Depo-SubQ Provera 104 (Medroxyprogesterone injection) for more than 2 years
- › Family history of osteoporosis
- › Chronic use of certain steroids and anti-seizure medicines
- › Anorexia nervosa
- › Chronic alcohol use
- › Smoking
- › Metabolic bone disease
Women who use Depo-SubQ Provera 104 (Medroxyprogesterone injection) are more like to experience calcium loss in their bones. This can lead to broken bones and osteoporosis. Your risk goes up the longer you are taking Depo-SubQ Provera 104 (Medroxyprogesterone injection). If you are taking Depo-SubQ Provera 104 (Medroxyprogesterone injection) for more than 2 years, your doctor will run tests to make sure your bones are still healthy.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Depo-SubQ Provera 104 (Medroxyprogesterone injection)
Final section. Do you want to return to drug navigation?- More effective than some other medicines for treating pain from endometriosis.