Dexilant

(dexlansoprazole)

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4.7/ 5 average rating with 73 reviewsforDexilant
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Treats heartburn.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Dexilant (dexlansoprazole) is an effective medicine to treat heartburn, but can be expensive since it is only available as a brand.

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  • Retail price
    $332.67
  • Savings
    11%
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Quick facts about Dexilant
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Relieves heartburn symptoms better than other stomach medicines (like Pepcid, Tagamet, and Zantac).
  • Lasts longer than other alternative stomach medicines.
  • Convenient once daily dosing.
  • Treats GERD in children 12 to 17 years of age.
  • Can be swallowed whole, or contents of the pill can be emptied into applesauce for easy swallowing.
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What to expect from Dexilant, on one page

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People’s experience with Dexilant

73reviews so far. What do you think?

Downsides

  • Similar to other proton pump inhibitors, Dexilant (dexlansoprazole) can weaken bones when taken for a long period of time.
  • Can take a few days before you start to feel the full effects.
  • Dexilant (dexlansoprazole) can affect how other medicines, vitamins, and minerals get absorbed in your body.
  • There's no generic version available, so it can be expensive.
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What to expect from Dexilant, on one page

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How it works

Dexilant (dexlansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach, which treats heartburn.

Quick facts about Dexilant
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Delayed-release pill
  • Dissolving tablet
People’s experience with Dexilant

73reviews so far. What do you think?

Prices and coupons

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What to expect when you take Dexilant (dexlansoprazole) for Erosive esophagitis and GERD

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Diarrhea
  • Abdominal pain
  • Nausea
  • Upper airway infection
  • Vomiting
  • Gas
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Side effect rates for Dexilant (dexlansoprazole)

From 1351 clinical trials of Dexilant when taken for erosive esophagitis and gerd (30 mg)
  • Diarrhea
    5%5%
    3%3%
  • Abdominal pain
    4%4%
    4%4%
  • Nausea
    3%3%
    3%3%
  • Upper airway infection
    3%3%
    1%1%
  • Gas
    3%3%
    1%1%
  • Vomiting
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Dexilant.

Dexilant (dexlansoprazole)
Placebo

People taking Dexilant felt side effect more

People taking Dexilant felt side effect less

No difference

Risks and Warnings for Dexilant (dexlansoprazole)

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  • Heartburn and feelings of upset stomach can be warning signs of more serious stomach problems or cancer. Call your doctor if you have throat pain, chest pain, belly pain, trouble swallowing, or signs of a bleeding ulcer such as black or bloody stools, or vomiting blood. These may be signs of a worse health problem.

Common concerns from people taking Dexilant (dexlansoprazole)

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Price
  • Worth it
    Worked well
    Low hassle
    Reviewed Dexilanton 8/23/2017Make sure to ask your doctor if they have discounts to offer; the manufacturer (Takeda) is still offering them, to my knowledge.
    32
    Man
    Two years or more
    Gastroesophageal reflux disease
  • Worth it
    Worked well
    Low hassle
    Reviewed Dexilanton 7/22/2016I have to take this every day. It really helps, but the cost is so much. Been trying to see how I can afford it.
    38
    Woman
    Gastroesophageal reflux disease
  • Worth it
    Worked well
    Low hassle
    Reviewed Dexilanton 8/16/2016There's a discount card from the manufacturer that if used with insurance brings the price to about $50, which is what I pay.
    35
    Woman
    Gastroesophageal reflux disease
Alcohol
  • Avoid drinking alcohol while taking the dissolving tablet.
  • Worth it
    Worked well
    Big hassle
    Reviewed Dexilanton 8/30/2016Take before acidic dinner/alcohol. Do not take with other meds in morning. Cancels out antidepressants.
    56
    Woman
    Gastroesophageal reflux disease
Food
  • Swallow Dexilant (dexlansoprazole) whole. Don't chew, break, or crush. If you can't swallow whole pills, you can sprinkle the contents of the pill in applesauce.
  • Take with or without food. Take the dissolving tablet 30 minutes before a meal.
  • Worth it
    Worked well
    Low hassle
    Reviewed Dexilanton 1/9/2017You can't take iron supplements with it so make sure you're getting enough with the food you eat.
    24
    Woman
    Heartburn
  • Worth it
    Worked well
    Low hassle
    Reviewed Dexilanton 4/19/2019All the other protein pump inhibitors caused me to be very sick. Couldn't eat hardly any food. Lost 60lbs from being sick.
    60
    Woman
    A year or so
    GERD
Kidneys and liver
  • Dexilant (dexlansoprazole) can cause kidney inflammation or kidney swelling. This kidney problem can occur at any time during treatment and is generally caused by an allergic reaction. Signs of kidney problems include inability to pass urine, changes in how much urine is passed, blood in the urine, or unexpected sudden weight gain.
Pain
  • Not sure
    Worked well
    Some hassle
    Reviewed Dexilanton 1/9/2017The medicine worked almost immediately at eliminating the acid causing blisters in my throat and pain in my stomach. It also helped my digestion. Less gas and healthier stools. After about a week of taking it I am so anxious and nervous. I feel like I drank 10 cups of coffee and every sound and touch is so irritating. I couldn't function I was so on-edge and angry.
    35
    Woman
    Gastroesophageal reflux disease