Migranal

(dihydroergotamine)

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Treats migraine headaches.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Migranal (dihydroergotamine) is not as good as other medicines to treat migraines because of side effects, but it can be an alternative if these haven't worked.

Lowest price near you
  • Price before coupon
    $2767.19
  • Lowest price with coupon
    $1502.03
  • Savings
    46%
Quick facts about dihydroergotamine
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (dihydroergotamine)

Upsides

  • If your migraines usually last more than 2 days, or if you have more frequent migraines,Migranal (dihydroergotamine) can work better than other medicines.
  • Migranal (dihydroergotamine) is available as a nasal spray or an injection, which is good if you're not able to swallow pills when you have migraines.
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What to expect from dihydroergotamine, on one page

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Downsides

  • Migranal (dihydroergotamine) can't prevent migraines from happening; it can only treat them.
  • Taking too much of Migranal (dihydroergotamine) over a period of time can be poisonous. Talk to your doctor if your headaches aren't getting better.
  • Migranal (dihydroergotamine) can only be used for migraines and cluster headaches. It won't work for tension headaches.
  • Not recommended for children.
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What to expect from dihydroergotamine, on one page

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How it works

Migranal (dihydroergotamine) is a medicine to treat migraines. Migraines are caused by opening of blood vessels in the brain. Migranal (dihydroergotamine) relieves the headache by tightening the blood vessels.

Quick facts about dihydroergotamine
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (dihydroergotamine)

Dosage forms

  • Nasal spray
  • Injection
Tried dihydroergotamine? Write a review!

Prices and coupons

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What to expect when you take Migranal (dihydroergotamine) for Migraine headache

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nose and throat irritation
  • Heart and lung problems
  • Blood vessel issues
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Side effect rates for Migranal (dihydroergotamine)

From 1228 clinical trials of dihydroergotamine when taken for migraine
  • Stuffy nose
    26%26%
    7%7%
  • Nausea
    10%10%
    4%4%
  • Changes in taste
    8%8%
    1%1%
  • Nasal irritation
    6%6%
    2%2%
  • Vomiting
    4%4%
    1%1%
  • Dizziness
    4%4%
    2%2%
  • Sore throat
    3%3%
    1%1%
  • Sleepiness
    3%3%
    2%2%
  • Diarrhea
    2%2%
    1%1%
  • Tingling or prickling sensation
    2%2%
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of dihydroergotamine.

Migranal (dihydroergotamine)
Placebo

People taking dihydroergotamine felt side effect more

People taking dihydroergotamine felt side effect less

No difference

Risks and Warnings for Migranal (dihydroergotamine)

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    • Higher risk if:
    • Macrolide antibiotics
    • Protease inhibitors

    Talk to your doctor or pharmacist right away if you're taking Migranal (dihydroergotamine) and you have to take macrolide antibiotics or medicines for HIV called protease inhibitors. Migranal (dihydroergotamine) can last a lot longer in the body if you take those medicines. You're at higher risk for stroke and less blood supply to your arms or legs if you take those medicines and Migranal (dihydroergotamine).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Migranal (dihydroergotamine)

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Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for dihydroergotamine
XUnsafe