Dipentum

(olsalazine)

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Treats ulcerative colitis, a chronic inflammatory condition involving your digestive system.

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Our bottom line

Dipentum (olsalazine) controls ulcerative colitis with other medicines, but you can't use it if you have a flare-up.

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    $1623.68
Quick facts about Dipentum
  • Drug class: gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Dipentum (olsalazine) is one of the few medicines you can take for ulcerative colitis by mouth.
  • Can stop your symptoms from coming back so often.
  • Take Dipentum (olsalazine) by itself or with rectal formulation. If you have tried taking other rectal formulations without success, taking Dipentum (olsalazine) with rectal formulation may provide relief.
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What to expect from Dipentum, on one page

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Downsides

  • Can be only used if you don't like enemas or similar dosage forms, but Dipentum (olsalazine) doesn't work as fast and you would have to take more pills.
  • Dipentum (olsalazine) can cause more side effects than other pills for ulcerative colitis. Talk to your doctor about oral alternatives with less side effects.
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What to expect from Dipentum, on one page

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How it works

Dipentum (olsalazine) lowers chemicals in the body that cause inflammation which are more common in ulcerative colitis.

Quick facts about Dipentum
  • Drug class: gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Dipentum? Write a review!

Prices and coupons

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What to expect when you take Dipentum (olsalazine) for Ulcerative Colitis

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  • First few hoursHours
    First few daysDays
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    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
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  • Possible side effects
  • Diarrhea
  • Abdominal pain and cramps
  • Nausea
  • Indigestion
  • Headache
  • Joint pain
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Side effect rates for Dipentum (olsalazine)

From 649 clinical trials of Dipentum when taken for ulcerative colitis
  • Diarrhea
    11%11%
    7%7%
  • Abdominal pain and cramps
    10%10%
    7%7%
  • Nausea
    5%5%
    4%4%
  • Headache
    5%5%
    5%5%
  • Indigestion
    4%4%
    4%4%
  • Joint pain
    4%4%
    3%3%
  • Bloating
    2%2%
    1%1%
  • Fatigue and drowsiness
    2%2%
    3%3%
  • Depression
    2%2%
  • Rash
    2%2%
    1%1%
  • Upper respiratory infection
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Dipentum.

Dipentum (olsalazine)
Placebo

People taking Dipentum felt side effect more

People taking Dipentum felt side effect less

No difference

Risks and Warnings for Dipentum (olsalazine)

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    • Higher risk if:
    • Allergy to salicylates

    Be sure to tell your doctor if you are allergic to salicylate medications (like aspirin). Symptoms of an allergic reaction can be mild like a rash, itchy skin, or hives, or be serious like trouble breathing or swelling of your face or mouth. If you have trouble breathing, go to the emergency room right away.

Common concerns from people taking Dipentum (olsalazine)

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Food
  • Take with food to avoid stomach upset.
Kidneys and liver
  • Rarely, Dipentum (olsalazine) can damage your kidneys. Your doctor might do regular blood tests if you have kidney problems.