doxepin

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Treats depression and anxiety.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

doxepin can treat depression and anxiety, but it's not a first choice medication because of its many side effects.

Lowest price near you
  • Price before coupon
    $13.19
  • Lowest price with coupon
    $10.46
  • Savings
    21%
Quick facts about doxepin
  • Drug class: Mental Health
  • Rx status: Prescription only
  • Generic status: Generic only

Upsides

  • doxepin has been consistently shown to improve symptoms of depression and anxiety.
  • doxepin has been used to treat depression for over forty years.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from doxepin, on one page

Download Fact Sheet
Tried doxepin? Write a review!

Downsides

  • doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
  • You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
  • You have to take it daily, especially if you are feeling better, for the medicine to do its job.
  • It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.
  • It's not unusual for people to try different antidepressants until they find one that works for them.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from doxepin, on one page

Download Fact Sheet
How it works

doxepin is a tricyclic antidepressant (TCA). It affects the levels of certain chemicals in the brain including serotonin and norepinephrine that can be out of balance during depression or anxiety.

Quick facts about doxepin
  • Drug class: Mental Health
  • Rx status: Prescription only
  • Generic status: Generic only

Dosage forms

  • Pill
  • Liquid
Tried doxepin? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 30 (10mg) capsules of doxepin near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take doxepin for Depression

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Drowsiness
  • Constipation
  • Dry mouth
  • Changes in blood pressure
  • Weight gain
  • Dizziness
Skip side effects section. Skip to risks and warnings section.

Side effect rates for doxepin

Risks and Warnings for doxepin

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Age 24 years or under

    doxepin, like other antidepressants, may increase the risk of suicidal thoughts or behavior, especially in children, teens, and young adults. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when your dose changes. Caregivers and family members should also watch out for these behavioral changes. Children under 12 years of age shouldn't take doxepin.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking doxepin

Final section. Do you want to return to drug navigation?
Alcohol
  • Avoid drinking alcohol while taking this medication.
  • You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
Sleep
  • Take doxepin at bedtime if it makes you drowsy. Avoid driving or doing other tasks or actions that call for you to be alert until you know how this medicine will affect you.
  • doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
Weight
  • It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.