Trulicity

(dulaglutide)

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Lowers your blood sugar.

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Our bottom line

Trulicity (dulaglutide) is a once-weekly injectable medicine that's used to control diabetes, but it can be expensive.

Lowest price near you
  • Price before coupon
    $821.02
  • Lowest price with coupon
    $632.06
  • Savings
    23%
Quick facts about Trulicity
  • Drug class: endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • May help with weight loss and controling appetite.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Dosed once a week compared to other injectables that have to be done daily.
  • Medicine is ready to use, without need to mix.
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What to expect from Trulicity, on one page

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Downsides

  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Many people taking Trulicity (dulaglutide) have upset stomach and side effects like nausea, vomiting, diarrhea, constipation, or indigestion.
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What to expect from Trulicity, on one page

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How it works

Trulicity (dulaglutide) is a medication for diabetes. It stimulates your body to make and release more insulin, stops the body from releasing more sugar, and slows down digestion.

Quick facts about Trulicity
  • Drug class: endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Injection
Tried Trulicity? Write a review!

Prices and coupons

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What to expect when you take Trulicity (dulaglutide) for Diabetes

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Diarrhea
  • Stomach pain
  • Low appetite
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Side effect rates for Trulicity (dulaglutide)

From 1402 clinical trials of Trulicity when taken for type 2 diabetes (1.5mg)
  • Low blood sugar
    35%35%
    30%30%
  • Nausea
    21%21%
    5%5%
  • Diarrhea
    13%13%
    7%7%
  • Vomiting
    13%13%
    2%2%
  • Low blood sugar
    11%11%
    2%2%
  • Stomach pain
    9%9%
    5%5%
  • Low appetite
    9%9%
    2%2%
  • Indigestion
    6%6%
    2%2%
  • Tiredness
    6%6%
    3%3%
  • Low blood sugar
    6%6%
    1%1%
  • Constipation
    4%4%
    1%1%
  • Acid reflux
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Trulicity.

Trulicity (dulaglutide)
Placebo

People taking Trulicity felt side effect more

People taking Trulicity felt side effect less

No difference

Risks and Warnings for Trulicity (dulaglutide)

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    • Higher risk if:
    • History of MTC
    • History of MEN 2

    Using Trulicity (dulaglutide) or other medicines similar to it might put you at higher risk for certain thyroid cancers. Let your doctor know if you or a family member have ever had thyroid cancer called medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia (MEN) syndrome type 2. Call your doctor right away if you have a neck mass, trouble breathing, trouble swallowing, or hoarseness that will not go away.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Trulicity (dulaglutide)

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Kidneys and liver
  • Trulicity (dulaglutide) can cause or worsen kidney damage. This is more likely to happen if you've had nausea or vomiting, diarrhea or dehydration. Make sure to drink plenty of fluids and stay hydrated when you're sick. If you have kidney damage already, your doctor might do regular lab tests while you're taking Trulicity (dulaglutide) to make sure your kidneys stay healthy.
  • No limitation for people with kidney problems, but close monitoring is recommended.
Weight
  • May help with weight loss and controling appetite.