Covaryx

(esterified estrogen / methyltestosterone)

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Relieves hot flashes due to menopause.

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Our bottom line

Covaryx (esterified estrogen / methyltestosterone) is an option if estrogen alone didn’t help relieve your hot flashes and night sweats, but there are more possible side effects from the androgen portion of the medicine.

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Quick facts about Covaryx
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (esterified estrogen / methyltestosterone)

Upsides

  • Can relieve menopause symptoms for some women that don't respond to estrogen therapy alone.
  • The small amout of androgen hormone may be good for your bones and libido. It also helps estrogen relieve the symptoms of menopause.
  • Available in 2 strengths, a half-strength and full-strength. Your doctor will start you at the lowest dose on a cyclic schedule (3 weeks on and 1 week off).
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Downsides

  • Not recommended as a first line choice for menopause symptoms.
  • Raises your risk of endometrial and breast cancer and for blood clots, DVT and stroke.
  • Can worsen your other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
  • Has some extra side effects that you don't get when taking estrogen alone.
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What to expect from Covaryx, on one page

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How it works

Covaryx (esterified estrogen / methyltestosterone) contains two hormones that work together to balance hormone changes in your body during and after menopause. Estrogen reduces hot flashes and night sweats. Methyltestosterone (an androgen) is believed to boost the effects of the estrogen.

Quick facts about Covaryx
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (esterified estrogen / methyltestosterone)

Used for

Dosage forms

  • Pill
Tried Covaryx? Write a review!

Prices and coupons

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What to expect when you take Covaryx (esterified estrogen / methyltestosterone) for Menopause symptoms

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
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  • Possible side effects
  • Menstrual changes
  • Nausea
  • Acne
  • Libido changes
  • Headache
  • Breast pain
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Side effect rates for Covaryx (esterified estrogen / methyltestosterone)

Risks and Warnings for Covaryx (esterified estrogen / methyltestosterone)

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    • Higher risk if:
    • › Using estrogen for more than one year

    If you're taking Covaryx (esterified estrogen / methyltestosterone) and have your uterus, you might have a higher risk of having endometrial cancer. Vaginal bleeding after menopause can be a warning sign, so let your doctor know if you notice any unusual bleeding. Using medicines like Covaryx (esterified estrogen / methyltestosterone) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Covaryx (esterified estrogen / methyltestosterone) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Covaryx (esterified estrogen / methyltestosterone)

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Pain
  • Covaryx (esterified estrogen / methyltestosterone) can raise your risk of blood clots, which can be very dangerous. You're more likely to have them if you smoke tobacco, are obese, or if you or your family have ever had blood clots. Get medical care right away if you have pain in your legs or arms, bad headaches, trouble breathing, or sudden changes in your speech or vision.
  • Go to the emergency room right away if you notice unusual swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision.
Sex
  • The small amout of androgen hormone may be good for your bones and libido. It also helps estrogen relieve the symptoms of menopause.
Weight
  • Can cause nausea, dizziness, bloating and breast tenderness.