Enbrel

(etanercept)

●●●●●
3.7/ 5 average rating with 90 reviewsforEnbrel
Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Calms down your immune system to prevent joint damage.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Enbrel (etanercept) effectively calms down your immune system, but it puts you at risk of serious infections.

Lowest price near you
  • Lowest price with coupon
    $5130.73
Find instant savings
Quick facts about Enbrel
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • People taking Enbrel (etanercept) for rheumatoid arthritis showed significant improvement and were able to reduce the dose or stop their other RA medicines.
  • Enbrel (etanercept) can work for you even if other medications didn't help your rheumatoid arthritis.
  • Enbrel (etanercept) is the first biologic approved for moderate to severe rheumatoid arthritis. Since it has been around for a long time, its side effects are well known.
  • Many people have only minor or no side effects.
  • It's available as a pre-filled syringe and SureClick auto-injector pen which some people find more convenient and easier to use.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Enbrel, on one page

Download Fact Sheet
People’s experience with Enbrel

90reviews so far. What do you think?

Downsides

  • Enbrel (etanercept) raises your risk of serious or life-threatening infections, including tuberculosis (TB).
  • Enbrel (etanercept) can increase the risk of lymphoma, leukemia and other cancers.
  • May not be the best choice if you have a history of heart failure or nervous system problems like multiple sclerosis.
  • You'll need to have regular blood tests before and during treatment to make sure you don't have any problems taking Enbrel (etanercept).
  • You could get injection site reactions such as redness, swelling, rash, itching, or bruising.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Enbrel, on one page

Download Fact Sheet
How it works

Enbrel (etanercept) blocks a protein called TNF (tumor necrosis factor) in the immune system which lowers inflammation, relieves symptoms and prevents disease progression.

Quick facts about Enbrel
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Injection
People’s experience with Enbrel

90reviews so far. What do you think?

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 1 (4-sureclicks-of-50mg) carton of Enbrel near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take Enbrel (etanercept) for Rheumatoid arthritis

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Injection site reactions
  • Infections
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Enbrel (etanercept)

From 1235 clinical trials of Enbrel when taken for plaque psoriasis
  • Any infection
    27%27%
    28%28%
  • Upper respiratory infections
    17%17%
    17%17%
  • Injection site reactions
    15%15%
    6%6%
  • Non-upper respiratory infections
    12%12%
    14%14%
  • Diarrhea
    3%3%
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Enbrel.

Enbrel (etanercept)
Placebo

People taking Enbrel felt side effect more

People taking Enbrel felt side effect less

No difference

Risks and Warnings for Enbrel (etanercept)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • › Latex allergy

    Rarely, Enbrel (etanercept) can cause allergic reactions that can be life-threatening. If you have hives, itching, trouble breathing, or lip, tongue, or throat swelling right after your dose or days later, call your doctor and get medical emergency care right away. You might need to stop taking Enbrel (etanercept). Inform your doctor if you have a latex allergy, as the SureClick Autoinjector has latex in the needle cover.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Enbrel (etanercept) questions for

Frequently Asked Questions

This medication treats ankylosing spondylitis.

Who is this drug for?

This medication treats ankylosing spondylitis.

Common concerns from people taking Enbrel (etanercept)

Final section. Do you want to return to drug navigation?
Alcohol
  • Worth it
    Worked so-so
    Low hassle
    Reviewed Enbrelon 9/17/2016Let it warm to room temperature before injecting 15-30min. Make sure the alcohol is dry before injecting or it will sting. It hurts less if you inject it into the stomach.
    44
    Woman
    Rheumatoid arthritis (moderate to severe)
Pain
  • Not sure
    Worked so-so
    Low hassle
    Reviewed Enbrelon 7/25/2017Inject in belly fat to lessen pain at site.
    56
    Woman
    A year or so
    Rheumatoid arthritis