Lithobid
(Lithium)
Stabilizes mood.
Our bottom line
Lithobid (Lithium) is the most effective long-term treatment for bipolar disorder, but it comes with a lot of side effects, so it can be difficult to take.
- Drug class: Mental health
- Rx status: Prescription only
- Generic status: Lower-cost generic available (lithium)
Upsides
- A first-line, long-term treatment for bipolar disorder. Effective at stabilizing mood and preventing relapse.
- For manic episodes (acute mania), more effective when taken together with an antipsychotic medicine.
- The only drug proven (so far) to lower the risk of suicide, possibly because it lowers aggressiveness and impulsivity.
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What to expect from Lithium, on one page
Downsides
- Has many short- and long-term side effects.
- The dose for it to work well is very close to the amount that causes overdose, so you have to be careful, watch out for symptoms, and get help immediately if you accidentally take too much.
- Probably not safe if you have kidney problems.
- Not safe to use if you're pregnant.
- Requires routine blood tests to see how the medicine is affecting your body.
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What to expect from Lithium, on one page
Researchers don't know exactly how Lithobid (Lithium) works, but it seems to affect chemicals in the brain that regulate mood.
- Drug class: Mental health
- Rx status: Prescription only
- Generic status: Lower-cost generic available (lithium)
Used for
Dosage forms
- Pill
- Extended release
- Oral solution
Prices and coupons
Skip prices section. Skip to what to expect section.- Get free coupon$13.58
- Get free coupon$13.58
What to expect when you take Lithobid (Lithium) for Bipolar disorder
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Starts to kick inFull effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Stomach problems
- Increased thirst
- Weight gain
- Skin problems
- Tremor
- Worse coordination
It can take time for a drug to start working, or for some side effects to go away.
Source: FDA product label and Iodine pharmacistsSide effect rates for Lithobid (Lithium)
Manufacturers don’t say how common these side effects are when taking Lithium for
- Tremor
- Muscle hyperirritability
- Ataxia
- Choreo-athetotic movements
- Hyperactive deep tendon reflexes
- Blackout spells
- Slurred speech
- Dizziness
- Vertigo
- Epileptiform seizures
- Somnolence
- Psychomotor retardation
- Restlessness
- Confusion
- Stupor
- Coma
- Acute Dystonia
- Downbeat Nystagmus
- Cardiac Arrhythmia
- Hypotension
- Peripheral Circulatory collapse
- Sinus node dysfunction with severe bradycardia
- Pseudotumor cerebri
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Albuminuria
- Oliguria
- Polyuria
- Glycosuria
- Drying and thinning of hair
- Anesthesia of skin
- Chronic Folliculitis
- Xerosis Cutis
- Alopeica
- Exacerbation of psoriasis
- Blurred vision
- Dry mouth
- Fatigue
- Lethargy
- Transient scotomata
- Dehydration
- Weight loss
- Tendency to sleep
- Headache
- Transient electroencephalographic and electrocardiographic changes
- Leucocytosis
- Diffuse non-toxic goiter
- Transient hyperglycemia
- Pruritus
- Cutaneous ulcers
- Albuminuria
- Worsening of organic brain syndromes
- Excessive weight gain
- Edematous swelling of ankles or wrists
- Thirst or polyuria
- Metallic taste
Risks and Warnings for Lithobid (Lithium)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Low sodium
- › Dehydration
- › Drug interactions (diuretics, ACE inhibitors, NSAIDs like ibuprofen)
The amount of Lithobid (Lithium) that's too much for your body to handle is only a little higher than the amount in an effective dose. This means it can be easy to accidentally overdose. Symptoms of Lithobid (Lithium) toxicity include diarrhea, vomiting, drowsiness, abnormal eye movements, muscle weakness, and lack of coordination. In severe cases, overdose can cause coma or seizures. If you think you've taken too much Lithobid (Lithium), stop taking it and seek medical attention immediately.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Lithobid (Lithium)
Final section. Do you want to return to drug navigation?Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.
Tip: Always talk with your doctor before you take any medication while pregnant.- Take with food or use extended release form to avoid stomach upset.
- Lithobid (Lithium) can reduce the kidney's ability to balance salt and water in your body. This is reversible if you stop taking Lithobid (Lithium). If you're urinating much more than usual, your doctor can do a blood test to check your kidney function.
- Probably not safe if you have kidney problems.
- The amount of Lithobid (Lithium) that's too much for your body to handle is only a little higher than the amount in an effective dose. This means it can be easy to accidentally overdose. Symptoms of Lithobid (Lithium) toxicity include diarrhea, vomiting, drowsiness, abnormal eye movements, muscle weakness, and lack of coordination. In severe cases, overdose can cause coma or seizures. If you think you've taken too much Lithobid (Lithium), stop taking it and seek medical attention immediately.
- Persistent stomach upset, slurred speech, or extreme drowsiness may be a sign that your dose is too high.
- Worth itSome hassleReviewed lithiumon 2/18/2018Do not take if you want to maintain your weight or lose weight unless others things are not working. It does work well on mood swings in some people44ManTwo years or moreWould rather not say
- Not worth itBig hassleReviewed Lithiumon 7/1/2017Try others before trying lithium if you are considering your weight.23WomanA few monthsBipolar disorder