Estrace

(Estradiol)

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Relieves hot flashes and vaginal symptoms related to menopause.

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Our bottom line

Estrace (Estradiol) treats symptoms of menopause, but causes more of side effects than other medicines like it.

Lowest price near you
  • Price before coupon
    $82.88
  • Lowest price with coupon
    $35.00
    58% savings
Quick facts about Estrace
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol)

Upsides

  • Estrace (Estradiol) comes as a pill and is much easier to use compared to the cream form.
  • Available as a cheaper, generic version.
  • Usually you only need to take DRUG NAME for a short amount of time.
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What to expect from Estrace, on one page

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Downsides

  • Associated with a higher risk for side effects like blood clots, stroke, and cancer compared to its cream formulation.
  • DRUG_ NAME can increase the risk of memory loss for women age 65 or older.
  • Your doctor might frequently change your dose of the medicine in the beginning until your symptoms are well-controlled.
  • Not recommended for women who need treatment only for vaginal dryness and itching.
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What to expect from Estrace, on one page

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How it works

Estrace (Estradiol) is a synthetic hormone called estradiol, which acts very similarly to estrogen. It replaces the estrogen lost during menopause to relieve hot flashes, vaginal dryness, and osteoporosis.

Quick facts about Estrace
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol)

Used for

  • Hot flashes
  • Vaginal dryness and inflammation
  • Low estrogen

Dosage forms

  • Pill
Tried Estrace? Write a review!

Prices and coupons

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What to expect when you take Estrace (Estradiol) for Ostoeporosis prevention

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
  • First few hoursHours
    First few daysDays
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  • Possible side effects
  • Nausea
  • Headache
  • Breast pain
  • Weight changes
  • Menstrual changes
  • High blood pressure
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Side effect rates for Estrace (Estradiol)

Risks and Warnings for Estrace (Estradiol)

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    • Higher risk if:
    • Using estrogen for more than one year

    Unusual vaginal bleeding during menopause can be a sign of cancer in the uterus. Let your doctor know if you notice any vaginal bleeding while on Estrace (Estradiol). The risk for cancer of the uterus increases the longer you're on this medicine. Talk to your doctor about other medicines you can take to protect yourself if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Estrace (Estradiol) questions for

Frequently Asked Questions

This medication treats vulvar and vaginal atrophy.

Who is this drug for?

This medication treats vulvar and vaginal atrophy.