Estraderm

(Estradiol Patch)

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Treats low estrogen, relieves menopause symptoms, and lowers your risk of osteoporosis.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

The Estraderm (Estradiol Patch) needs to be replaced twice a week, and it may have fewer side effects than oral estrogen pills.

Lowest price near you
  • Price before coupon
    $82.88
  • Lowest price with coupon
    $35.00
    58% savings
Quick facts about Estradiol Patch
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)

Upsides

  • The Estraderm (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • The patch is good for people who don't want to take daily pills.
  • Can be worn while swimming, bathing, and showering.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
  • Improves mood, energy, and mental alertness for some people.
Tried Estradiol Patch? Write a review!

Downsides

  • Only comes in 2 strengths.
  • You need to replace the Estraderm (Estradiol Patch) twice a week, compared to other patches that are once a week.
  • Patch can fall off.
  • Increases your risk of uterine and breast cancer.
  • If you have your uterus, you have to use the Estraderm (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
How it works

The Estraderm (Estradiol Patch) replaces an estrogen hormone, estradiol, that your body loses during and after menopause. Higher levels of estradiol relieve symptoms of low estrogen and menopause and prevent bone loss.

Quick facts about Estradiol Patch
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (estradiol patch)

Used for

  • Hot flashes and night sweats
  • Vaginal dryness and inflammation
  • Low estrogen

Dosage forms

  • Patch
Tried Estradiol Patch? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 1 (8-twice-weekly-patches-of-0.05mg-day) carton of estradiol near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Estraderm (Estradiol Patch)

From 266 clinical trials of Estradiol Patch when taken for estrogen replacement postmenopause (0.1 mg/day)
  • Breast pain
    28%28%
    4%4%
  • URTI
    17%17%
    8%8%
  • Abdominal pain
    16%16%
    8%8%
  • Headache
    13%13%
    10%10%
  • Pain
    11%11%
    7%7%
  • Edema
    10%10%
    6%6%
  • Back pain
    9%9%
    6%6%
  • Depression
    8%8%
  • Flatulence
    7%7%
    1%1%
  • Leukorrhea
    7%7%
    1%1%
  • Pharyngitis
    7%7%
    3%3%
  • Nausea
    6%6%
    3%3%
  • Rhinitis
    6%6%
    1%1%
  • Arthralgia
    5%5%
    3%3%
  • Sinusitis
    5%5%
    3%3%
  • Pruritus
    3%3%
    6%6%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Estradiol Patch.

Estraderm (Estradiol Patch)
Placebo

People taking Estradiol Patch felt side effect more

People taking Estradiol Patch felt side effect less

No difference

Risks and Warnings for Estraderm (Estradiol Patch)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. When estrogen is prescribed to women after menopause who still have a uterus, progestin should be used with it to lower the risk of cancer. Low-dose vaginal estrogen products are often a better choice than oral pills for women 65 years or older who have vaginal symptoms.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Estraderm (Estradiol Patch)

Final section. Do you want to return to drug navigation?
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Estradiol Patch
XUnsafe
Weight
  • Can cause nausea, dizziness, bloating, and breast tenderness.