Estring

(estradiol vaginal ring)

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3.3/ 5 average rating with 56 reviewsforEstring
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Relieves vaginal dryness due to menopause.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Estring (estradiol vaginal ring) is more convenient than other forms of estrogen therapy since you only have to replace it every 3 months, but it needs to be inserted directly into the vagina.

Lowest price near you
  • Price before coupon
    $617.08
  • Lowest price with coupon
    $459.61
  • Savings
    26%
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Quick facts about Estring
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Many women find Estring (estradiol vaginal ring) more comfortable to use and easier to apply than creams or gels.
  • Estring (estradiol vaginal ring) may be more convenient since it is dosed once every 3 months compared to alternatives that need to taken daily or twice weekly.
  • Works directly at the site of application and safer than oral estrogen pills.
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What to expect from Estring, on one page

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People’s experience with Estring

56reviews so far. What do you think?

Downsides

  • Estring (estradiol vaginal ring) may not be the best option if you have a narrow vagina or frequent vaginal infections.
  • The ring can fall out without you noticing.
  • Estring (estradiol vaginal ring) is only available as brand name, so can be expensive.
  • Estring (estradiol vaginal ring) All estrogen therapies increase your risk for uterine cancer, heart problems, and blood clots.
Get our free fact sheet

What to expect from Estring, on one page

Download Fact Sheet
How it works

Estring (estradiol vaginal ring) acts like estrogen to restore functions lost when hormone levels are dramatically reduced during menopause.

Quick facts about Estring
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Vaginal dryness and inflammation

Dosage forms

  • Vaginal ring
People’s experience with Estring

56reviews so far. What do you think?

Prices and coupons

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What to expect when you take Estring (estradiol vaginal ring) for Vaginal dryness and inflammation

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Headache
  • Vaginal discharge
  • Yeast infection
  • Vaginal discomfort/pain
  • Vaginal inflammation
  • Back pain
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Side effect rates for Estring (estradiol vaginal ring)

From 257 clinical trials of Estring when taken for vaginal dryness and inflammation
  • Headache
    13%13%
  • Vaginal discharge
    7%7%
  • Back pain
    6%6%
  • Yeast infection
    6%6%
  • Upper airway infection
    5%5%
  • Vaginal inflammation
    5%5%
  • Vaginal discomfort/pain
    5%5%
  • Arthritis
    4%4%
  • Trouble sleeping
    4%4%
  • Stomach pain
    4%4%
  • Sinus infection
    4%4%
  • Vaginal bleeding
    4%4%
  • Bacterial growth in the genitals
    4%4%
  • Joint pain
    3%3%
  • Nausea
    3%3%
  • Flu-like symptoms
    3%3%
  • Bone pain
    2%2%
  • Bladder infection
    2%2%
  • Hot flashes
    2%2%
  • Stress
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Estring.

Estring (estradiol vaginal ring)
Placebo

People taking Estring felt side effect more

People taking Estring felt side effect less

No difference

Risks and Warnings for Estring (estradiol vaginal ring)

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    • Higher risk if:
    • › Using estrogen for more than one year
    • › Higher dose of estrogen

    Taking Estring (estradiol vaginal ring) for more than 1 year increases your risk for uterine cancer. Talk to your doctor if this concerns you. Let your doctor know if you notice any unusual bleeding while on Estring (estradiol vaginal ring).

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Estring (estradiol vaginal ring) questions for

Frequently Asked Questions

This medication treats moderate to severe urogenital symptoms associated with postmenopausal vaginal atrophy.

Who is this drug for?

This medication treats moderate to severe urogenital symptoms associated with postmenopausal vaginal atrophy.

Common concerns from people taking Estring (estradiol vaginal ring)

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Pain
  • Not sure
    Worked so-so
    Low hassle
    Reviewed Estringon 9/10/2016Love the convenience still have issues, burning pain
    69
    Woman
    Vaginal dryness and inflammation
Weight
  • Not worth it
    Didn’t work
    Big hassle
    Reviewed Estringon 8/4/2019weight gain, bloating, discomfort
    66
    Woman
    Less than a week
    Vaginal dryness and inflammation