Evista

(Raloxifene)

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Prevents bone loss and lowers your risk of breast cancer.

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Our bottom line

Evista (Raloxifene) is effective at reducing bone loss and lowering the risk of breast cancer in postmenopausal women, but does carry the risk of blood clots.

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    $31.80
Quick facts about Evista
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (raloxifene)

Upsides

  • Evista (Raloxifene) doesn’t affect the breast or uterus the same way that estrogen does, so the risk of cancer is much lower.
  • Taking Evista (Raloxifene) with calcium and vitamin D improves spine and hip bone health and lowers the risk of fractures.
  • Lowers total cholesterol and low-density lipoprotein (LDL) cholesterol (the bad cholesterol).
Tried Evista? Write a review!

Downsides

  • Can only take Evista (Raloxifene) once you’re in menopause. You can't take it if you're pregnant or breastfeeding.
  • Evista (Raloxifene) isn’t as effective as tamoxifen at lowering the risk of invasive breast cancer.
  • Shouldn’t take it with any other forms of estrogen (pills, patches, or injection).
  • It doesn’t increase bone strength as much as estrogen does and isn’t effective for treating hot flashes.
How it works

Evista (Raloxifene) is a selective estrogen receptor modulator (SERM). It acts like estrogen to make your bones stronger and less likely to break, and also protects breast and uterus tissues from other estrogen effects.

Quick facts about Evista
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (raloxifene)
Tried Evista? Write a review!

Prices and coupons

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Side effect rates for Evista (Raloxifene)

From 10101 clinical trials of Evista when taken for osteoporosis (60 mg)
  • Any side effect
    25%25%
    24%24%
  • Peripheral edema
    14%14%
    12%12%
  • Muscle spasms/leg cramps
    12%12%
    8%8%
  • Hot Flashes
    8%8%
    5%5%
  • Cholelithiasis
    3%3%
    3%3%
  • Venous thromboembolic events
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Evista.

Evista (Raloxifene)
Placebo

People taking Evista felt side effect more

People taking Evista felt side effect less

No difference

Risks and Warnings for Evista (Raloxifene)

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    • Higher risk if:
    • History of stroke
    • Heart and blood vessel problems
    • History of mini stroke (TIA)
    • Atrial fibrillation
    • Smoking
    • High blood pressure

    Evista (Raloxifene) can cause increase the risk of stroke. The risk is greater in women with a history of stroke or TIA, who have heart disease, atrial fibrillation, high blood pressure and who smoke.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Evista (Raloxifene) questions for

Frequently Asked Questions

This medication prevents and treats osteoporosis for in women who have already gone through menopause.

Who is this drug for?

This medication prevents and treats osteoporosis for in women who have already gone through menopause.

Common concerns from people taking Evista (Raloxifene)

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Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Evista
XUnsafe
Alcohol
  • Regular exercise, cutting back on smoking, and drinking less alcohol can also reduce your risk of bone loss.
Food
  • Take 1 tablet daily with or without food about the same time each day. It’s important to read the information you get with your medicine about how to take Evista (Raloxifene).
Kidneys and liver
  • Evista (Raloxifene) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need a different dose.