Gilenya

(fingolimod)

3.0/ 5 average rating with 57 reviewsforGilenya
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Treats relapsing forms of multiple sclerosis.

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Our bottom line

Gilenya (fingolimod) reduces the number of flare-ups, new brain lesions, and physical changes in relapsing MS, but it has many side effects.

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Quick facts about Gilenya
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Gilenya (fingolimod) is the first once-daily pill you can take for relapsing forms of MS.
  • Gilenya (fingolimod) lowers relapse rates and the number of new MS lesions better than the leading injectable.
  • Gilenya (fingolimod) takes up to 2 months to leave your body, which is much shorter than another oral medication Aubagio(teriflunomide), which can take up to 2 years.
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What to expect from Gilenya, on one page

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People’s experience with Gilenya

57reviews so far. What do you think?

Downsides

  • Gilenya (fingolimod) takes up to 2 months to leave your body – much longer than a similar medication, Tecfidera (dimethyl fumarate), which takes only a few hours.If you haven't had chickenpox or been vaccinated for it yet, you'll need to get the vaccine at least 1 month before starting Gilenya (fingolimod).
  • Gilenya (fingolimod) might not be a good choice if you have kidney, liver, or heart problems.
  • If you've stopped taking Gilenya (fingolimod) for 2 weeks or more, you'll have to take your first dose at your doctor's office when restarting.
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What to expect from Gilenya, on one page

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How it works

Gilenya (fingolimod) is an immune modulator. It blocks your white blood cells from attacking the nerves in your brain and spinal cord.

Quick facts about Gilenya
  • Drug class: Autoimmune
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
People’s experience with Gilenya

57reviews so far. What do you think?

Prices and coupons

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What to expect when you take Gilenya (fingolimod) for Multiple sclerosis

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Headache
  • Nausea
  • Diarrhea
  • Cough
  • Flu infection
  • Sinus infection
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Side effect rates for Gilenya (fingolimod)

From 1556 clinical trials of Gilenya when taken for multiple sclerosis (.5 mg)
  • Headache
    25%25%
    24%24%
  • Abnormal liver blood tests
    15%15%
    4%4%
  • Nausea
    13%13%
    12%12%
  • Diarrhea
    13%13%
    10%10%
  • Cough
    12%12%
    11%11%
  • Flu infection
    11%11%
    8%8%
  • Sinus infection
    11%11%
    8%8%
  • Stomach pain
    11%11%
    10%10%
  • Back pain
    10%10%
    9%9%
  • Pain in arms or legs
    10%10%
    7%7%
  • Shortness of breath
    9%9%
    7%7%
  • Bronchitis
    8%8%
    5%5%
  • High blood pressure
    8%8%
    4%4%
  • Migraine
    6%6%
    4%4%
  • Blurred vision
    4%4%
    2%2%
  • Low blood pressure
    3%3%
    1%1%
  • Hair loss
    3%3%
    2%2%
  • Herpes viral infections
    2%2%
    1%1%
  • Fungal skin infection
    2%2%
    1%1%
  • Weakness
    2%2%
    1%1%
  • Scaly skin
    2%2%
    1%1%
  • Low white blood cells
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Gilenya.

Gilenya (fingolimod)
Placebo

People taking Gilenya felt side effect more

People taking Gilenya felt side effect less

No difference

Risks and Warnings for Gilenya (fingolimod)

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    • Higher risk if:
    • Taking other medicines that slow heart rate
    • History of heart problems

    It’s important to take the first dose of Gilenya (fingolimod) in a medical facility with doctors monitoring how you react to it. Gilenya (fingolimod) can cause your heart rate to slow down, especially in the first 6 to 24 hours after your first dose. Your heart rate should return to normal within 1 month after you start Gilenya (fingolimod). If you have a history of any heart condition, discuss the risks and benefits of using Gilenya (fingolimod) with your doctor. Call your doctor or get medical care right away if you have a slow heart rate, dizziness, tiredness, or if you feel like your heart is skipping beats.

Common concerns from people taking Gilenya (fingolimod)

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Food
  • Take 1 capsule daily with or without food.
Kidneys and liver
  • Gilenya (fingolimod) might not be a good choice if you have kidney, liver, or heart problems.