Flexeril

(cyclobenzaprine)

3.5/ 5 average rating with 1064 reviewsforFlexeril
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Relaxes your muscles.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.

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    $283.93
Quick facts about Flexeril
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cyclobenzaprine)

Upsides

  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women, but talk to your doctor about it first.
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What to expect from Flexeril, on one page

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People’s experience with Flexeril

1064reviews so far. What do you think?

Downsides

  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
  • Can make you have dry mouth.
  • Not effective for muscle spasms caused by brain or spinal injuries.
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What to expect from Flexeril, on one page

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How it works

Flexeril (cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.

Quick facts about Flexeril
  • Drug class: Musculoskeletal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (cyclobenzaprine)

Dosage forms

  • Pill
  • Liquid
People’s experience with Flexeril

1064reviews so far. What do you think?

Prices and coupons

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What to expect when you take Flexeril (cyclobenzaprine) for Muscle relaxant

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Drowsiness
  • Dry mouth
  • Constipation
  • Headache
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Side effect rates for Flexeril (cyclobenzaprine)

From 255 clinical trials of Flexeril when taken for muscle spasms (extended release - 15 mg)
  • Dry mouth
    6%6%
    2%2%
  • Dizziness
    3%3%
    2%2%
  • Fatigue
    3%3%
    2%2%
  • Nausea
    3%3%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Flexeril.

Flexeril (cyclobenzaprine)
Placebo

People taking Flexeril felt side effect more

People taking Flexeril felt side effect less

No difference

Risks and Warnings for Flexeril (cyclobenzaprine)

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    • Higher risk if:
    • Taking monoamine oxidase inhibitors (MAOI)
    • Taking other medications for your mood

    Taking Flexeril (cyclobenzaprine) along with other medications used for your mood can make you more likely to have a serious condition called serotonin syndrome. Monoamine oxidase inhibitors should not be used with Flexeril (cyclobenzaprine), and need to be stopped at least 14 days before starting Flexeril (cyclobenzaprine). Symptoms of serotonin syndrome include confusion, hallucinations, tremors, seizure, nausea, vomiting, and diarrhea. Go to the emergency room or talk to your doctor immediately if you notice these symptoms. Talk to your doctor or pharmacist about all the medicines you are taking including prescription, over the counter, and supplements to make sure there are no interactions.

Common concerns from people taking Flexeril (cyclobenzaprine)

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Pain
  • Can relieve pain associated with muscle spasms.
  • Not worth it
    Big hassle
    Reviewed Flexerilon 8/19/2017I felt like it would relax my muscles too much thus making my body feel very weak and in more pain. I switched to tizanidine 2mg and feel much better. The doctors say that you have to use the muscle relaxer with the opiate. But also if there's pain usually there's immflamation.
    36
    Woman
    Two years or more
    Fibromyalgia
Sleep
  • Taking Flexeril (cyclobenzaprine) may make you feel dizzy or sleepy for the first few days. Avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
  • Flexeril (cyclobenzaprine) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Worth it
    Low hassle
    Reviewed cyclobenzaprineon 10/22/2017Take at night when you first start taking it, may make you drowsy. I took cyclobenzaprine which is the generic version for Flexeril, both made me feel the same way.
    26
    Woman
    Just as needed
    Muscle spasm
  • Worth it
    Low hassle
    Reviewed Flexerilon 7/27/2017Take it at night 30min before you go to sleep
    25
    Woman
    Just as needed
    Muscle spasm
  • Not sure
    Low hassle
    Reviewed Flexeril5mg dosages are similar in effectiveness and don't cause as much drowsiness or dry mouth. While only the dry mouth was an issue for me after the first week it would have been nice to know that I could have started at a lower dose.
    29
    Woman
Weight
  • Not sure
    Low hassle
    Reviewed Flexerilcaused dry mouth and weight gain
    58
    Woman