Arixtra

(fondaparinux)

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Thins the blood and treats blood clots.

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Our bottom line

Arixtra (fondaparinux) is effective at treating clots, but it can increase your risk of bleeding.

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    $1104.23
Quick facts about Arixtra
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fondaparinux)

Upsides

  • Arixtra (fondaparinux) is effective at treating blood clots in the extremeties and those that have travelled to the lungs.
  • A generic form is available.
  • Arixtra (fondaparinux) is a safe option for use in patients who have experienced a rare, life-threatening reaction to another anticoagulant, heparin.
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What to expect from Arixtra, on one page

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Downsides

  • Arixtra (fondaparinux) should be used with caution in patients with kidney problems, as this can lead to an accumulation of the medication and increase the risk of bleeding.
  • Arixtra (fondaparinux) can cause a drop in platelet count, which can increase your risk of bleeding.
  • People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when taking Arixtra (fondaparinux).
  • Periodic blood tests and monitoring of your kidneys is important.
  • You have to inject yourself everyday with this medication.
  • The anti blood-clotting effects of Arixtra (fondaparinux) may remain for up to 4 days after stopping this medication in normal patients, and there is no current antidote.
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What to expect from Arixtra, on one page

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How it works

Arixtra (fondaparinux) inhibits factor Xa, a component of the blood clotting pathway that prevents blood clot formation.

Quick facts about Arixtra
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (fondaparinux)

Used for

  • Treatment of blood clots
  • Revascularization following heart attack
  • Treatment of other blood clots

Dosage forms

  • Injection
Tried Arixtra? Write a review!

Prices and coupons

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What to expect when you take Arixtra (fondaparinux) for Treatment or prevention of blood clots

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Anemia
  • Difficulty sleeping
  • Post-operative bleeding
  • Injection site bleeding
  • Rash
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Side effect rates for Arixtra (fondaparinux)

From 327 clinical trials of Arixtra when taken for extended prophylaxis
  • Major bleeding
    2%2%
  • Bleeding index >/= 2
    2%2%
  • Minor bleeding
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Arixtra.

Arixtra (fondaparinux)
Placebo

People taking Arixtra felt side effect more

People taking Arixtra felt side effect less

No difference

Risks and Warnings for Arixtra (fondaparinux)

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    • Higher risk if:
    • Indwelling epidural catheters
    • Use of other medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or other anticoagulants
    • History of traumatic or repeated epidural or spinal puncture
    • History of spinal surgery

    Arixtra (fondaparinux) can cause spinal/epidural bloot clots if you are also receiving anesthesia or undergoing spinal procedures. These blood clots may result in long-term or permanent paralysis. You will be monitored frequently for signs and symptoms of impaired mental function, such as partial or complete paralysis, muscle weakness, loss of sensation, or pain. If you notice any of these symptoms, contact your doctor immediately.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Arixtra (fondaparinux) questions for

Frequently Asked Questions

This medication prevents deep vein thrombosis in people undergoing surgery, including hip fracture surgery, hip replacement surgery, knee replacement surgery and abdominal surgery who are at risk for thromboembolic complications.

Who is this drug for?

This medication prevents deep vein thrombosis in people undergoing surgery, including hip fracture surgery, hip replacement surgery, knee replacement surgery and abdominal surgery who are at risk for thromboembolic complications.

Common concerns from people taking Arixtra (fondaparinux)

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Price
  • Arixtra (fondaparinux) can cause a drop in platelet count, which can increase your risk of bleeding.
Interactions
  • Arixtra (fondaparinux) can cause many interactions, talk with your doctor before starting any new drug, including prescription or over-the-counter, natural products, or vitamins.
Kidneys and liver
  • Arixtra (fondaparinux) can cause further complications with existing bleeding, heart infection, or poor kidney function. Talk to your doctor before starting this medication if you have any of these conditions.
  • Arixtra (fondaparinux) should be used with caution in patients with kidney problems, as this can lead to an accumulation of the medication and increase the risk of bleeding.
  • Periodic blood tests and monitoring of your kidneys is important.