Glyxambi

(empaglifozin / linagliptin)

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Lowers blood sugar.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Glyxambi (empaglifozin / linagliptin) is a combination drug that lowers the number of pills you have to take, but may be more expensive than the individual components.

Lowest price near you
  • Retail price
    $654.90
  • Savings
    15%
Quick facts about Glyxambi
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Lowers A1c levels by 1.0-1.5%.
  • Can cause weight loss.
  • Taken once daily.
  • Can lower the risk of death in those with underlying heart disease.
Get our free fact sheet

What to expect from Glyxambi, on one page

Download Fact Sheet
Tried Glyxambi? Write a review!

Downsides

  • May not be good for people who have kidney problems.
  • Not available as a generic, so can be more expensive than other diabetes medications.
  • Can increase likelihood of urinary tract or yeast infections.
  • May cause you to urinate more frequently throughout the day.
Get our free fact sheet

What to expect from Glyxambi, on one page

Download Fact Sheet
How it works

Glyxambi (empaglifozin / linagliptin) contains 2 anti-diabetes medicines. Empagliflozin lowers blood sugar by increasing secretion of blood sugar into your urine, while linagliptin helps your body produce more insulin and less glucagon.

Quick facts about Glyxambi
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Glyxambi? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 30 (25mg-5mg) tablets of Glyxambi near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take Glyxambi (empaglifozin / linagliptin) for Type 2 diabetes

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Urinary tract infection
  • Common cold
  • Upper respiratory tract infection
  • Low blood sugar
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Glyxambi (empaglifozin / linagliptin)

From 272 clinical trials of Glyxambi when taken for type 2 diabetes (empagliflozin 10 mg + linagliptin 5 mg)
  • Urinary tract infection
    13%13%
  • Upper respiratory tract infection
    7%7%
  • Common cold
    6%6%
  • Low blood sugar
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Glyxambi.

Glyxambi (empaglifozin / linagliptin)
Placebo

People taking Glyxambi felt side effect more

People taking Glyxambi felt side effect less

No difference

Risks and Warnings for Glyxambi (empaglifozin / linagliptin)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Kidney problems
    • Liver problems
    • Alcohol use
    • Age 65 or older
    • Surgery
    • Contrast Dye
    • Congestive heart failure
    • Calorie restriction

    Glyxambi (empaglifozin / linagliptin) may cause a dangerous build up of acid in your body, known as ketoacidosis. Stop taking Glyxambi (empaglifozin / linagliptin) and contact your doctor right away if you experience nausea, vomiting, abdominal pain, tiredness, or trouble breathing.

Common concerns from people taking Glyxambi (empaglifozin / linagliptin)

Final section. Do you want to return to drug navigation?
Food
  • Take in the morning by mouth with or without food.
Kidneys and liver
  • Rarely, Glyxambi (empaglifozin / linagliptin) can hurt the kidneys. This is more likely to happen if you already have kidney damage, heart failure, or take certain medicines for blood pressure or anti-inflammatories (NSAIDs). Your doctor will check your kidneys by blood tests regularly, and might ask you to change how you take Glyxambi (empaglifozin / linagliptin).
  • May not be good for people who have kidney problems.
Weight
  • Can cause weight loss.