granisetron

Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Helps prevent nausea and vomiting due to chemotherapy or radiation treatment

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

granisetron is a safe and effective medication used for preventing nausea and vomiting due to chemotherapy and radiation, but it can be very expensive.

Lowest price near you
  • Lowest price with coupon
    $123.13
Quick facts about granisetron
  • Drug class: gastrointestinal
  • Rx status: Prescription only
  • Generic status: Generic only

Upsides

  • granisetron is effective even for those who are using chemotherapy that is associated with a high risk for causing nausea and vomiting.
  • Safe and effective option for older people, unlike some other alternatives.
  • You only need to take granisetron on the days you actually receive chemotherapy and radiation.
  • A patch form of the medication is available for those who don't want to or who are unable to take pills.
  • Safe to use for people with kidney problems.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from granisetron, on one page

Download Fact Sheet
Tried granisetron? Write a review!

Downsides

  • granisetron only prevents symptoms of nausea and vomiting so you must take the medication before you get chemotherapy or radiation treatment.
  • Can affect the natural rhythm of your heart, especially if you take other medications that can also potentially cause the same problem.
  • Might not be a good option for those who are on certain antidepressants.
  • granisetron is very expensive compared to similar alternatives.
  • Very likely to cause side effects like headache and constipation.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from granisetron, on one page

Download Fact Sheet
How it works

granisetron is 5_HT3 receptor antagonist. It prevents nausea and vomiting by blocking the receptors in your brain that the neurotransmitter called serotonin normally binds to.

Quick facts about granisetron
  • Drug class: gastrointestinal
  • Rx status: Prescription only
  • Generic status: Generic only

Used for

  • Prevention of chemotherapy-associated nausea and vomiting
  • Prevention of radiation-associated nausea and vomiting
  • Prevention of post-surgery nausea and vomiting

Dosage forms

  • Pill
Tried granisetron? Write a review!

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 60 (1mg) tablets of granisetron near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take granisetron for Prevention of nausea and vomiting due to chemotherapy

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Constipation
  • Weakness
  • Diarrhea
  • Stomach pain
  • Indigestion
Skip side effects section. Skip to risks and warnings section.

Side effect rates for granisetron

From 1635 clinical trials of granisetron when taken for prevention of nausea and vomiting due to chemotherapy (2 mg once a day)
  • Headache
    20%20%
    12%12%
  • Weakness
    18%18%
    4%4%
  • Constipation
    14%14%
    8%8%
  • Diarrhea
    9%9%
    4%4%
  • Indigestion
    6%6%
    4%4%
  • Stomach pain
    4%4%
    3%3%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of granisetron.

granisetron
Placebo

People taking granisetron felt side effect more

People taking granisetron felt side effect less

No difference

Risks and Warnings for granisetron

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • Taking other medications that also affect serotonin levels in the brain

    granisetron can cause serotonin syndrome, a rare but serious problem caused by abnormally high levels of serotonin, which is a chemical messenger found in the brain. You have a higher risk of experiencing serotonin syndrome if you also take other medications that increase serotonin levels such as certain classes of anti-depressants like SSRI's. Symptoms of serotonin syndrome include agitation, mental confusion, hallucinations, high fever, fast heartbeat, muscle stiffness, tremors, and sweating. Get medical help right away and stop taking granisetron if you experience any of those symptoms.

Common concerns from people taking granisetron

Final section. Do you want to return to drug navigation?
Kidneys and liver
  • Safe to use for people with kidney problems.