Imitrex

(Sumatriptan)

3.9/ 5 average rating with 31 reviewsforImitrex
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Treats migraine headaches.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.

Lowest price near you
  • Price before coupon
    $49.99
  • Lowest price with coupon
    $11.76
    76% savings
Quick facts about Imitrex
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sumatriptan)

Upsides

  • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
  • A combination of forms can be used if symptoms do not improve.
  • The nasal spray and injectable forms work very quickly.
  • It's generally safe to use if you are pregnant.
  • Comes in a generic form, so it can be pretty cheap.
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What to expect from Imitrex, on one page

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People’s experience with Imitrex

31reviews so far. What do you think?

Downsides

  • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
  • Does not prevent migraine headaches; it only treats them once they start.
  • Must wait 1 hour before using second injection.
  • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
  • Need to have your blood pressure checked often, especially if you're pregnant.
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Get our free fact sheet

What to expect from Imitrex, on one page

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How it works

Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.

Quick facts about Imitrex
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (sumatriptan)

Dosage forms

  • Pill
  • Injection
  • Nasal spray
People’s experience with Imitrex

31reviews so far. What do you think?

Prices and coupons

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What to expect when you take Imitrex (Sumatriptan) for Migraine Headache

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Dizziness
  • Palpitations
  • Diarrhea
  • Skin reaction (injection)
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Side effect rates for Imitrex (Sumatriptan)

From 726 clinical trials of Imitrex when taken for migraine attacks (25 mg)
  • Pain and other pressure sensations
    6%6%
    4%4%
  • Atypical sensations
    5%5%
    4%4%
  • Paresthesia (all types)
    3%3%
    2%2%
  • Sensation warm/cold
    3%3%
    2%2%
  • Pain - location specified
    2%2%
    1%1%
  • Malaise/fatigue
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Imitrex.

Imitrex (Sumatriptan)
Placebo

People taking Imitrex felt side effect more

People taking Imitrex felt side effect less

No difference

Risks and Warnings for Imitrex (Sumatriptan)

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    • Higher risk if:
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking

    Some people taking Imitrex (Sumatriptan) have reported temporary chest pain, pressure, and tightness. These symptoms are caused by heart vessels being constricted/tightened. Before starting Imitrex (Sumatriptan), people who have coronary artery disease, or are more likely to have it, should talk to their doctor about having a heart health assessment.

Pharmacist Q&A

Imitrex (Sumatriptan) questions for

Frequently Asked Questions

This medication treats migraine attacks.

Who is this drug for?

This medication treats migraine attacks.

Common concerns from people taking Imitrex (Sumatriptan)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Imitrex
CWeigh risks vs. benefits
Pain
  • Worth it
    Some hassle
    Reviewed Imitrexon 8/31/2017Clear your schedule for the day, but worth it to get out of pain that would have ruined your day anyway
    29
    Woman
    Just as needed
    Migraine headache
  • Worth it
    Low hassle
    Reviewed Imitrexon 8/23/2017Better than taking pain medications to get rid of your migraine.
    33
    Man
    Two years or more
    Migraine headache
  • Worth it
    Low hassle
    Reviewed Imitrexon 9/30/2016I used to wait until I knew the pain was a migraine, but it took so much longer to work, now I take it at the first sign. For the last year or so, I get tired after taking it, unless I'm up and moving around, but it's better than the pain!
    41
    Woman
    Migraine headache
Sleep
  • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.