Invokana

(canagliflozin)

4.0/ 5 average rating with 27 reviewsforInvokana
Skip to: drug prices sectionSkip to: what to expect sectionSkip to: side effects sectionSkip to: risks and warnings sectionSkip to: common concerns from users and pharmacists
ADVERTISEMENT

Lowers blood sugar.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Invokana (canagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.

Lowest price near you
  • Retail price
    $542.90
  • Savings
    13%
Quick facts about Invokana
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Lowers A1C (blood sugar) levels by 1%.
  • You only have to take Invokana (canagliflozin) once a day before meals.
  • Less likely to cause low blood sugar than other diabetes medicines.
  • Also available as a combination drug with metformin (Invokamet).
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Invokana, on one page

Download Fact Sheet
People’s experience with Invokana

27reviews so far. What do you think?

Downsides

  • You're more likely to have broken bones, yeast infections and urinary tract infections with Invokana (canagliflozin).
  • There's a rare but serious risk of leg and foot amputations with Invokana (canagliflozin). Talk to your doctor if you develop new pain or infections in your feet.
  • Not for people with severe kidney problems.
  • Can raise your cholesterol.
  • Avoid if you are a heavy drinker of alcohol.
Get the newsletter!

Sign up and get Pill Talk, the latest in health & medicine news from Iodine

Get our free fact sheet

What to expect from Invokana, on one page

Download Fact Sheet
How it works

Invokana (canagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.

Quick facts about Invokana
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
People’s experience with Invokana

27reviews so far. What do you think?

Prices and coupons

Skip prices section. Skip to what to expect section.
Prices and coupons for 30 (300mg) tablets of Invokana near
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
See more prices and coupons in your area

What to expect when you take Invokana (canagliflozin) for Type 2 diabetes

Skip what to expect section. Skip to side effects section.
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Urinary tract infections
  • Yeast infections
  • Dehydration
  • Low blood pressure
  • Increased urination
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Invokana (canagliflozin)

From 737 clinical trials of Invokana when taken for type 2 diabetes (100 mg)
  • Yeast infection in women
    11%11%
    3%3%
  • Urinary tract infections
    6%6%
    4%4%
  • Increased urination
    5%5%
    1%1%
  • Yeast infection in men
    4%4%
    1%1%
  • Thirst
    3%3%
  • Vaginal itching
    2%2%
  • Constipation
    2%2%
    1%1%
  • Nausea
    2%2%
    2%2%
  • Abdominal pain
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Invokana.

Invokana (canagliflozin)
Placebo

People taking Invokana felt side effect more

People taking Invokana felt side effect less

No difference

Risks and Warnings for Invokana (canagliflozin)

Skip risks section. Skip to common concerns section.
    • Higher risk if:
    • History of amputations 
    • Peripheral vascular disease (narrowed blood vessels)
    • Nerve problems
    • Diabetic foot ulcers 

    Rarely, Invokana (canagliflozin) can increase your risk of getting foot or leg amputations. Let your doctor know if you experience any new pain, tenderness, sores, ulcers, or infections on your legs or feet.

Common concerns from people taking Invokana (canagliflozin)

Final section. Do you want to return to drug navigation?
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Invokana
CWeigh risks vs. benefits
Price
  • Worth it
    Low hassle
    Reviewed Invokanaon 7/3/2017It works really well for me, but because of the cost and the fact my health insurance wont cover it...I can't continue to take it. It made me lose 40 lbs in 2 months without any additional exercise. The $500.00 price range is just way too much for me right now.
    51
    Man
    A few months
    Type 2 diabetes
Alcohol
  • Avoid if you are a heavy drinker of alcohol.
Food
  • Take once daily before your first meal of the day.
  • You only have to take Invokana (canagliflozin) once a day before meals.
Kidneys and liver
  • Not for people with severe kidney problems.
Pain
  • Rarely, Invokana (canagliflozin) can hurt the kidneys. This is more likely to happen if you already have kidney damage, heart failure, or take certain medicines for blood pressure or anti-inflammatories (NSAIDs). Invokana (canagliflozin) can also lower your blood pressure since it makes you urinate more. Your doctor will check your kidneys by blood tests regularly, and might ask you to change how you take Invokana (canagliflozin). Make sure to stay hydrated to prevent low blood pressure and kidney problems.
Weight
  • Not worth it
    Low hassle
    Reviewed Invokanaon 9/6/2016I actually gained weight with this,
    60
    Woman
    Type 2 diabetes