Cresemba

(isavuconazonium)

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Treats serious fungal infections.

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Our bottom line

Cresemba (isavuconazonium) is used to treat serious fungal infections as an alternative if you had problems with first choice medicines. However, it can be very expensive.

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  • Lowest price with coupon
    $4864.52
Quick facts about Cresemba
  • Drug class: infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Unlike some other antifungal medications, you don’t need regular blood tests while you're taking Cresemba (isavuconazonium).
  • Cresemba (isavuconazonium) has fewer and milder side effects than other medicines for fungal infections.
  • You only need to take Cresemba (isavuconazonium) once a day after the first two days.
  • If you have conditions related to a slow or abnormal heartbeat, Cresemba (isavuconazonium) may be a good choice for treatment of a serious fungal infection.
  • Available in both an injectable form and capsules you take by mouth.
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What to expect from Cresemba, on one page

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Downsides

  • Cresemba (isavuconazonium) needs to be taken twice daily.
  • Cresemba (isavuconazonium) may cause serious blood, muscle and liver problems.
  • Cresemba (isavuconazonium) is not recommended if you have kidney damage.
  • Cresemba (isavuconazonium) has a high incidence of side effects, including nausea, vomiting, loss of appetite, headache and malaise.
  • Cresemba (isavuconazonium) can negatively affect your cholesterol and blood sugar levels.
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What to expect from Cresemba, on one page

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How it works

Cresemba (isavuconazonium) is an antibiotic, isuvaconazonium, that kills fungal infections by weakening its cells and stops the fungus from protecting itself.

Quick facts about Cresemba
  • Drug class: infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Invasive aspergillosis
  • Invasive mucormycosis

Dosage forms

  • Pill
  • Injection
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Prices and coupons

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What to expect when you take Cresemba (isavuconazonium) for Serious fungal infections

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  • Effectiveness
  • Full effects
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  • Possible side effects
  • Nausea
  • Vomiting
  • Nausea, vomiting, diarrhea
  • Headache
  • Change in liver blood tests
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Side effect rates for Cresemba (isavuconazonium)

From 237 clinical trials of Cresemba when taken for aspergillosis or mucormycosis
  • Nausea
    28%28%
  • Vomiting
    25%25%
  • Diarrhea
    24%24%
  • Low potassium
    19%19%
  • Abdominal pain
    17%17%
  • Headache
    17%17%
  • Changes in liver blood tests
    17%17%
  • Trouble breathing
    17%17%
  • Swelling in the arms and legs
    15%15%
  • Constipation
    14%14%
  • Insomnia
    11%11%
  • Fatigue
    11%11%
  • Kidney failure
    10%10%
  • Back pain
    10%10%
  • Chest pain
    9%9%
  • Decreased appetite
    9%9%
  • Confusion/delirium
    9%9%
  • Skin rash
    9%9%
  • Itching
    8%8%
  • Low blood pressure
    8%8%
  • Anxiety
    8%8%
  • Acute respiratory failure
    7%7%
  • Indigestion
    6%6%
  • Injection site reactions
    6%6%
  • Low magnesium
    5%5%
0%
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80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Cresemba.

Cresemba (isavuconazonium)
Placebo

People taking Cresemba felt side effect more

People taking Cresemba felt side effect less

No difference

Risks and Warnings for Cresemba (isavuconazonium)

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  • Cresemba (isavuconazonium) can cause abnormal liver blood tests and some liver conditions which will usually go away once you finish Cresemba (isavuconazonium). Your doctor will do blood tests to check your liver regularly while you're taking Cresemba (isavuconazonium). Let your doctor know right away if you notice any yellowing of the skin or eyes, upper abdominal pain, loss of appetite, or dark urine.

Common concerns from people taking Cresemba (isavuconazonium)

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Interactions
  • Cresemba (isavuconazonium) has a lot of drug interactions that can affect how well it works. Before you start Cresemba (isavuconazonium), always let your doctor and pharmacist know all of the medications you’re taking including over the counter medications and herbal supplements.
Kidneys and liver
  • Cresemba (isavuconazonium) can cause liver problems. Let your doctor know if you notice yellowing of the skin or eyes, upper abdominal pain, or dark urine.
  • Cresemba (isavuconazonium) is not recommended if you have kidney damage.