Isentress

(raltegravir)

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Works with other medicications to treat HIV infection.

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Our bottom line

Isentress (raltegravir) is considered a first choice to be used with other medications for treating HIV, but it can have more side effects than other similar medicines.

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    $1498.05
Quick facts about Isentress
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Isentress (raltegravir) is a first choice treatment to use together with other medications to treat HIV.
  • If you have difficulty swallowing the tablet, there is a chewable tablet or oral suspension available.
  • Can be used by children 4 weeks and older.
  • People with mild to moderate kidney or liver damage can use Isentress (raltegravir).
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What to expect from Isentress, on one page

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Downsides

  • It might be hard to remember to take Isentress (raltegravir) two times a day. Other similar medicines are once a day.
  • The chewable tablets contain phenylalanine and should be avoided in people who have phenylketonuria.
  • Isentress (raltegravir) cannot be used alone to treat or prevent HIV. It must be used together with other medications.
  • Not available as part of a combination tablet, so you'll have to take more tablets daily compared to other combinations.
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What to expect from Isentress, on one page

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How it works

Isentress (raltegravir) is an integrase inhibitor. It treats or prevents HIV by stopping the virus from reproducing within cells in your immune system.

Quick facts about Isentress
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

Dosage forms

  • Pill
  • Chewable tablet
  • Liquid
Tried Isentress? Write a review!

Prices and coupons

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What to expect when you take Isentress (raltegravir) for HIV treatment

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
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  • Possible side effects
  • Rash
  • Nausea
  • Headache
  • Fatigue
  • Insomnia
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Side effect rates for Isentress (raltegravir)

From 281 clinical trials of Isentress when taken for hiv treatment (400mg)
  • Headache
    4%4%
  • Insomnia
    4%4%
  • Nausea
    3%3%
  • Fatigue
    2%2%
  • Dizziness
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Isentress.

Isentress (raltegravir)
Placebo

People taking Isentress felt side effect more

People taking Isentress felt side effect less

No difference

Risks and Warnings for Isentress (raltegravir)

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    • Higher risk if:
    • Prior severe allergic reaction to Isentress

    Some people taking Isentress (raltegravir) have had severe and potentially life-threatening skin reactions. If you suddenly get a high fever, blistering rash all over your body, oral lesions, or trouble breathing, go to the emergency room right away.

Pharmacist Q&A

Isentress (raltegravir) questions for

Frequently Asked Questions

This medication, in combination with other antiretroviral agents, treats HIV-1 infection in adults and children (2+).

Who is this drug for?

This medication, in combination with other antiretroviral agents, treats HIV-1 infection in adults and children (2+).

Common concerns from people taking Isentress (raltegravir)

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Kidneys and liver
  • People with mild to moderate kidney or liver damage can use Isentress (raltegravir).
Pain
  • Isentress (raltegravir) might cause muscle pain, weakness, or damage in some patients, which can also cause kidney damage if it's not caught in time. If you have any of these symptoms or notice dark urine, to your doctor immediately.