Ninlaro

(ixazomib)

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Treats multiple myeloma.

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Our bottom line

Ninlaro (ixazomib) is an effective medication for multiple myeloma in people who have received at least one other therapy, but it can have serious side effects.

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    $9880.95
Quick facts about Ninlaro
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • First oral medication of its kind, and easy to take as a weekly capsule.
  • Studies showed that people taking Ninlaro (ixazomib) had slower disease progression and improved response.
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What to expect from Ninlaro, on one page

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Downsides

  • Not a good choice if you are pregnant or planning on getting pregnant, as it can cause harm to your unborn baby.
  • In rare cases, Ninlaro (ixazomib) can lead to serious side effects including liver, stomach, and nerve problems; preexisting liver or kidney conditions may increase risk.
  • Because certain medications can interfere with Ninlaro (ixazomib), it is important your doctor is aware of all medications you are taking.
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What to expect from Ninlaro, on one page

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How it works

Ninlaro (ixazomib) is a proteasome inhibitor, which triggers cancer cells to self-destruct.

Quick facts about Ninlaro
  • Drug class: cancer
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Multiple myeloma, relapsed disease

Dosage forms

  • Capsule
Tried Ninlaro? Write a review!

Prices and coupons

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What to expect when you take Ninlaro (ixazomib) for Multiple myeloma

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
    Long term
  • Possible side effects
  • Upper airway infection
  • Weakness in hands and/or feet
  • Diarrhea
  • Constipation
  • Nausea
  • Increased risk of bleeding
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Side effect rates for Ninlaro (ixazomib)

From 720 clinical trials of Ninlaro when taken for multiple myeloma
  • Increased risk of bleeding
    78%78%
    54%54%
  • Low white blood cell count
    67%67%
    66%66%
  • Diarrhea
    42%42%
    36%36%
  • Constipation
    34%34%
    25%25%
  • Weakness in hands and/or feet
    28%28%
    21%21%
  • Nausea
    26%26%
    21%21%
  • Swelling in legs
    25%25%
    18%18%
  • Vomiting
    22%22%
    11%11%
  • Back pain
    21%21%
    16%16%
  • Upper airway infection
    19%19%
    14%14%
  • Rash
    19%19%
    11%11%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Ninlaro.

Ninlaro (ixazomib)
Placebo

People taking Ninlaro felt side effect more

People taking Ninlaro felt side effect less

No difference

Risks and Warnings for Ninlaro (ixazomib)

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    • Higher risk if:
    • History of liver problems
    • History of kidney problems
    • Kidney dialysis

    In rare cases, Ninlaro (ixazomib) can lead to liver injury. Talk to your doctor if you notice yellowing of skin or whites of your eyes or pain in your right abdominal area. Your doctor will check your liver regularly with blood tests.

Common concerns from people taking Ninlaro (ixazomib)

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Kidneys and liver
  • In rare cases, Ninlaro (ixazomib) can lead to serious side effects including liver, stomach, and nerve problems; preexisting liver or kidney conditions may increase risk.
Pain
  • In rare cases, Ninlaro (ixazomib) can lead to liver injury. Talk to your doctor if you notice yellowing of skin or whites of your eyes or pain in your right abdominal area. Your doctor will check your liver regularly with blood tests.
  • Ninlaro (ixazomib) can cause tingling, pain, numbness, burning sensation, or weakness in your arms or legs. Talk to your doctor if you experience new or worsening symptoms.