Zestril

(lisinopril)

3.8/ 5 average rating with 687 reviewsforLisinopril
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Lowers blood pressure.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

Lowest price near you
  • Lowest price with coupon
    $499.09
Quick facts about Lisinopril
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (lisinopril)

Upsides

  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
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What to expect from Lisinopril, on one page

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People’s experience with Lisinopril

687reviews so far. What do you think?

Downsides

  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
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What to expect from Lisinopril, on one page

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How it works

Zestril (lisinopril) is an angiotensin converting enzyme (ACE) inhibitor. It blocks a chemical that tightens blood vessels. This makes blood vessels relax, which lowers blood pressure and allows more blood and oxygen to get to your heart and other organs.

Quick facts about Lisinopril
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (lisinopril)

Dosage forms

  • Pill
  • Liquid
People’s experience with Lisinopril

687reviews so far. What do you think?

Prices and coupons

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What to expect when you take Zestril (lisinopril) for High blood pressure

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Dizziness
  • Headache
  • Kidney problems
  • High potassium levels
  • Cough
  • Unusual swelling
Skip side effects section. Skip to risks and warnings section.

Side effect rates for Zestril (lisinopril)

  • Low blood pressure
    5%5%
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Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Lisinopril.

Zestril (lisinopril)
Placebo

People taking Lisinopril felt side effect more

People taking Lisinopril felt side effect less

No difference

Risks and Warnings for Zestril (lisinopril)

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    • Higher risk if:
    • Women of childbearing age

    Zestril (lisinopril) can cause birth defects. If you find you're pregnant, stop taking Zestril (lisinopril) right away and talk to your doctor.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Zestril (lisinopril)

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Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Lisinopril
DWeigh risks vs. benefits
Kidneys and liver
  • You'll need to have blood tests done to check your kidney function.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
Pain
  • Not worth it
    Big hassle
    Reviewed Lisinoprilon 5/26/2017never had chest pain was taken in for a stint then put on heart meds Tired of all the side effects and damage these drugs will cause to other body organs. I have become weak, tired, dizzy, cough, headaches. Have high blood pressure which I never had before. Drugs suck. Side effects and precautions. Night mare waiting.
    69
    Woman
    Two years or more
    Heart attack
Sleep
  • Not sure
    Big hassle
    Reviewed Lisinoprilon 8/27/2016It will make you sleepy!I took a very low dose, 2.5 mg., to protect my kidney function from lupus. I had to get off it due to a life-threatening, but comical, allergic reaction: angio-edema causing facial swelling.
    47
    Woman
    High blood pressure