Lomotil
(diphenoxylate / atropine)
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Stops diarrhea.
Skip Upsides & Downsides section. Skip to side effects section.
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Our bottom line
Lomotil (diphenoxylate / atropine) is very effective at stopping diarrhea, but shouldn't be used for all types of diarrhea.
Quick facts about Lomotil
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (diphenoxylate / atropine)
Upsides
- Available as a cheaper, generic form.
- Available in both liquid and tablets.
- Is more effective than over-the-counter options for diarrhea and works very fast.
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Downsides
- May have to take this medication 3 to 4 times a day for full effect.
- Cannot use if you have diarrhea caused by an infection, or if you have ulcerative colitis or jaundice.
- Children less than 6 years old are more vulnerable to serious side effects of Lomotil (diphenoxylate / atropine) including slowed breathing, coma, and delirium.
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What to expect from Lomotil, on one page
Download Fact SheetHow it works
Lomotil (diphenoxylate / atropine) is a combination medication that helps stop diarrhea by slowing the movement of your intestines.
Quick facts about Lomotil
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (diphenoxylate / atropine)
Used for
Dosage forms
- Pill
- Liquid
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Prices and coupons
Skip prices section. Skip to what to expect section.Prices and coupons for 30 (2.5mg-0.025mg) tablets of diphenoxylate / atropine near
- CostcoGet free coupon$14.00
- Kroger PharmacyGet free coupon$14.50
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See more prices and coupons in your areaWhat to expect when you take Lomotil (diphenoxylate / atropine) for Diarrhea
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Full effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Allergic reactions
- Constipation
- Difficulty urinating
- Rapid heart beat
- Depression
- Blurred vision
Side effect rates for Lomotil (diphenoxylate / atropine)
Risks and Warnings for Lomotil (diphenoxylate / atropine)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Taking diuretics
- › Not drinking enough fluids
- › Severe diarrhea
Diarrhea can make you dehydrated. Lomotil (diphenoxylate / atropine) can help with diarrhea, but won't correct any electrolyte or fluid abnormalities you may experience from diarrhea. Talk to your doctor or pharmacist about dehydration and how to treat it.
Common concerns from people taking Lomotil (diphenoxylate / atropine)
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- Lomotil (diphenoxylate / atropine) can make you feel sleepy or dizzy and it can lower your ability to focus, think, and react. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.