Lomotil
(diphenoxylate / atropine)
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Stops diarrhea.
Skip Upsides & Downsides section. Skip to side effects section.
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Our bottom line
Lomotil (diphenoxylate / atropine) is very effective at stopping diarrhea, but shouldn't be used for all types of diarrhea.
Lowest price near you
- Price before coupon$17.90
- Lowest price with coupon$12.83
- Savings28%
Quick facts about Lomotil
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (diphenoxylate / atropine)
Upsides
- Available as a cheaper, generic form.
- Available in both liquid and tablets.
- Is more effective than over-the-counter options for diarrhea and works very fast.
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Downsides
- May have to take this medication 3 to 4 times a day for full effect.
- Cannot use if you have diarrhea caused by an infection, or if you have ulcerative colitis or jaundice.
- Children less than 6 years old are more vulnerable to serious side effects of Lomotil (diphenoxylate / atropine) including slowed breathing, coma, and delirium.
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What to expect from Lomotil, on one page
How it works
Lomotil (diphenoxylate / atropine) is a combination medication that helps stop diarrhea by slowing the movement of your intestines.
Quick facts about Lomotil
- Drug class: Gastrointestinal
- Rx status: Prescription only
- Generic status: Lower-cost generic available (diphenoxylate / atropine)
Used for
Dosage forms
- Pill
- Liquid
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Prices and coupons
Skip prices section. Skip to what to expect section.Prices and coupons for 30 (2.5mg-0.025mg) tablets of diphenoxylate / atropine near
- Pay as low as$7.91Retail priceRetail priceLearn more
- Kroger PharmacyGet free coupon$12.83
- Get free discount$14.41
- Rite AidGet free coupon$14.50
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
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See more prices and coupons in your areaWhat to expect when you take Lomotil (diphenoxylate / atropine) for Diarrhea
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Full effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Allergic reactions
- Constipation
- Difficulty urinating
- Rapid heart beat
- Depression
- Blurred vision
It can take time for a drug to start working, or for some side effects to go away.
Source: FDA product label and Iodine pharmacistsSide effect rates for Lomotil (diphenoxylate / atropine)
Manufacturers don’t say how common these side effects are when taking Lomotil for diarrhea
- Numbness in the arms & legs
- Euphoria
- Depression
- Tiredness
- Confusion
- Drowsiness
- Dizziness
- Restlessness
- Headache
- Allergic reactions
- Abnormal swelling of intestines (toxic megacolon)
- Intestinal blockage (paralytic ileus)
- Pancreatic inflammation
- Vomiting
- Nausea
- Lack of appetite
- Abdominal discomfort
- Difficulty urinating
- Overheating
- Rapid heart beat
- Flushing
- Dryness of the skin
- Constipation
- Blurred vision
Risks and Warnings for Lomotil (diphenoxylate / atropine)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Taking diuretics
- › Not drinking enough fluids
- › Severe diarrhea
Diarrhea can make you dehydrated. Lomotil (diphenoxylate / atropine) can help with diarrhea, but won't correct any electrolyte or fluid abnormalities you may experience from diarrhea. Talk to your doctor or pharmacist about dehydration and how to treat it.
Common concerns from people taking Lomotil (diphenoxylate / atropine)
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- Lomotil (diphenoxylate / atropine) can make you feel sleepy or dizzy and it can lower your ability to focus, think, and react. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.