Lomotil

(diphenoxylate / atropine)

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Stops diarrhea.

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Lomotil (diphenoxylate / atropine) is very effective at stopping diarrhea, but shouldn't be used for all types of diarrhea.

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Quick facts about Lomotil
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (diphenoxylate / atropine)

Upsides

  • Available as a cheaper, generic form.
  • Available in both liquid and tablets.
  • Is more effective than over-the-counter options for diarrhea and works very fast.
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Downsides

  • May have to take this medication 3 to 4 times a day for full effect.
  • Cannot use if you have diarrhea caused by an infection, or if you have ulcerative colitis or jaundice.
  • Children less than 6 years old are more vulnerable to serious side effects of Lomotil (diphenoxylate / atropine) including slowed breathing, coma, and delirium.
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How it works

Lomotil (diphenoxylate / atropine) is a combination medication that helps stop diarrhea by slowing the movement of your intestines.

Quick facts about Lomotil
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (diphenoxylate / atropine)

Used for

Dosage forms

  • Pill
  • Liquid
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Prices and coupons

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What to expect when you take Lomotil (diphenoxylate / atropine) for Diarrhea

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  • Effectiveness
  • Full effects
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  • Possible side effects
  • Allergic reactions
  • Constipation
  • Difficulty urinating
  • Rapid heart beat
  • Depression
  • Blurred vision
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Side effect rates for Lomotil (diphenoxylate / atropine)

Risks and Warnings for Lomotil (diphenoxylate / atropine)

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    • Higher risk if:
    • Taking diuretics
    • Not drinking enough fluids
    • Severe diarrhea

    Diarrhea can make you dehydrated. Lomotil (diphenoxylate / atropine) can help with diarrhea, but won't correct any electrolyte or fluid abnormalities you may experience from diarrhea. Talk to your doctor or pharmacist about dehydration and how to treat it.

Common concerns from people taking Lomotil (diphenoxylate / atropine)

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Sleep
  • Lomotil (diphenoxylate / atropine) can make you feel sleepy or dizzy and it can lower your ability to focus, think, and react. Avoid activities that require you to be alert, such as driving a car or operating machinery, until you know how this medication affects you.