Lopid

(gemfibrozil)

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Lowers cholesterol and triglyceride levels.

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Our bottom line

Lopid (gemfibrozil) works well to lower triglycerides and bad cholesterol, but it may not be the best option if you're also on a statin drug.

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Quick facts about Lopid
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (gemfibrozil)

Upsides

  • Lopid (gemfibrozil) is available as a generic.
  • It can significantly lower your triglycerides and bad cholesterol (LDL), and raise your good cholesterol (HDL).
  • More effective and causes fewer side effects than non-statin cholesterol-lowering medicines.
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What to expect from Lopid, on one page

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Downsides

  • Since so many people use statin medications to treat their cholesterol, Lopid (gemfibrozil) isn't generally the first choice treatment to use since it can interact with statins.
  • Can be more expensive than some alternative medicines.
  • Need to take Lopid (gemfibrozil) twice a day, whereas other similar medications are only once a day.
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What to expect from Lopid, on one page

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How it works

Lopid (gemfibrozil) is a fibric acid that lowers the levels of triglycerides and bad cholesterol in your blood, while raising the levels of good cholesterols.

Quick facts about Lopid
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (gemfibrozil)

Dosage forms

  • Pill
Tried Lopid? Write a review!

Prices and coupons

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What to expect when you take Lopid (gemfibrozil) for High cholesterol and triglycerides

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Stomach upset
  • Abdominal pain
  • Diarrhea
  • Fatigue
  • Nausea or vomiting
  • Eczema
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Side effect rates for Lopid (gemfibrozil)

From 4081 clinical trials of Lopid when taken for high cholesterol and triglycerides
  • Stomach and intestinal problems
    34%34%
    24%24%
  • Stomach upset
    20%20%
    12%12%
  • Abdominal pain
    10%10%
    6%6%
  • Diarrhea
    7%7%
    7%7%
  • Fatigue
    4%4%
    4%4%
  • Nausea or vomiting
    3%3%
    2%2%
  • Eczema
    2%2%
    1%1%
  • Rash
    2%2%
    1%1%
  • Feeling off balance
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Lopid.

Lopid (gemfibrozil)
Placebo

People taking Lopid felt side effect more

People taking Lopid felt side effect less

No difference

Risks and Warnings for Lopid (gemfibrozil)

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    • Higher risk if:
    • Taking Lopid (gemfibrozil) with statins

    People taking Lopid (gemfibrozil) have had muscle pain, which have led to muscle and kidney damage. The risk is higher if you're also taking a statin medication. Talk to your doctor if you develop sudden muscle pain, weakness, tenderness, or brown urine.

Common concerns from people taking Lopid (gemfibrozil)

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Alcohol
  • Check with your doctor before you drink alcohol.
Food
  • People on blood thinners, such as Coumadin, and also taking Lopid (gemfibrozil) may be at higher risk of bleeding. Your doctor may have you get lab work done more frequently, or may adjust the dose of your blood thinner.
  • Take Lopid (gemfibrozil) 30 minutes before breakfast and dinner everyday.
Kidneys and liver
  • Lopid (gemfibrozil) may not be right for some people with kidney problems. Let your doctor know if you have a history of kidney problems.
Weight
  • It's important to maintain a healthy weight, so try to exercise 3 to 4 times a week, for 40 minutes each time.