Ludiomil

(maprotiline)

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Stabilizes your mood.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

While Ludiomil (maprotiline) is part of the first choice of medicines to treat depression, it can cause drowsiness and dehydration.

Quick facts about maprotiline
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (maprotiline)

Upsides

  • Ludiomil (maprotiline) is available in generic.
  • Ludiomil (maprotiline) doesn't cause sleep problems, unlike other medicines used to treat depression.
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What to expect from maprotiline, on one page

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Downsides

  • Ludiomil (maprotiline) can make you very drowsy compared to other similar medicines.
  • Ludiomil (maprotiline) can cause weight gain, fainting, and make you feel dehydrated.
  • Stopping Ludiomil (maprotiline) suddenly without telling your doctor can be dangerous.
  • You might not notice changes in your mood until you've taken Ludiomil (maprotiline) for several weeks.
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What to expect from maprotiline, on one page

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How it works

Ludiomil (maprotiline) is a tricyclic antidepressant. It raises the amount of norepinephrine in the brain, which is believed to be one of the chemicals that regulates mood.

Quick facts about maprotiline
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (maprotiline)

Used for

Dosage forms

  • Pill
Tried maprotiline? Write a review!

Prices and coupons

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Prices and coupons for 270 (50mg) tablets of maprotiline near
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What to expect when you take Ludiomil (maprotiline) for Depression

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Drowsiness
  • Dry mouth
  • Higher risk of infections
  • Heart problems
  • Dizziness
  • Constipation
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Side effect rates for Ludiomil (maprotiline)

  • Dry mouth
    22%22%
  • Drowsiness
    16%16%
  • Dizziness
    8%8%
  • Constipation
    6%6%
  • Nervousness
    6%6%
  • Weakness & fatigue
    4%4%
  • Headache
    4%4%
  • Vision changes
    4%4%
  • Anxiety
    3%3%
  • Difficulty controlling movements
    3%3%
  • Trouble sleeping
    2%2%
  • Nausea
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of maprotiline.

Ludiomil (maprotiline)
Placebo

People taking maprotiline felt side effect more

People taking maprotiline felt side effect less

No difference

Risks and Warnings for Ludiomil (maprotiline)

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    • Higher risk if:
    • People under age 24

    Taking Ludiomil (maprotiline) can make you more likely to harm yourself or commit suicide, especially if you are younger and during the first few weeks of taking the medicine. If you or your child feel like they want to hurt themselves while taking Ludiomil (maprotiline), call the doctor right away.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Ludiomil (maprotiline) questions for

Frequently Asked Questions

This medication treats depression.

Who is this drug for?

This medication treats depression.

Common concerns from people taking Ludiomil (maprotiline)

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Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for maprotiline
BProbably safe
Weight
  • Ludiomil (maprotiline) can cause weight gain, fainting, and make you feel dehydrated.