Delzicol

(mesalamine)

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Treats ulcerative colitis and helps prevent flares.

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Our bottom line

Delzicol (mesalamine) effectively reduces symptoms of a flare for mild to moderate ulcerative colitis in both children and adults, but can cause burping and stomach discomfort.

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    $430.74
Quick facts about Delzicol
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Delzicol (mesalamine) effectively treats ulcerative colitis flares.
  • This drug is often used as the first-choice treatment in adults and children.
  • If you have trouble swallowing the drug whole, the pill can be opened and you can swallow the tablets inside.
  • Can be used in children 5 years and older.
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What to expect from Delzicol, on one page

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Downsides

  • Treatment dosage must be taken 3 times a day for a total of 6 weeks.
  • Can take a few weeks before you start to feel the effects.
  • Delzicol (mesalamine) is not available as a cheaper, generic form.
  • Combination therapy with oral and rectal forms may be needed for some people.
  • This form of mesalamine isn't used for maintenance, only to help reduce flare symptoms.
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What to expect from Delzicol, on one page

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How it works

The exact mechanism of action for Delzicol (mesalamine) remains somewhat unknown. It appears to reduce inflammation in the colon by interfering with the local immune system, and its action appears to be local rather than systemic.

Quick facts about Delzicol
  • Drug class: Gastrointestinal
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Delayed-release pill
Tried Delzicol? Write a review!

Prices and coupons

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What to expect when you take Delzicol (mesalamine) for Ulcerative colitis (adults)

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Burping
  • Abdominal pain
  • Constipation
  • Dizziness
  • Runny nose
  • Back pain
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Side effect rates for Delzicol (mesalamine)

From 105 clinical trials of Delzicol when taken for ulcerative colitis (adults) (2.4 g/day)
  • Burping
    26%26%
    19%19%
  • Abdominal pain
    21%21%
    12%12%
  • Constipation
    11%11%
  • Dizziness
    9%9%
    8%8%
  • Runny nose
    8%8%
    6%6%
  • Back pain
    6%6%
    4%4%
  • Rash
    6%6%
    4%4%
  • Upset stomach
    4%4%
  • Flu syndrome
    4%4%
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Delzicol.

Delzicol (mesalamine)
Placebo

People taking Delzicol felt side effect more

People taking Delzicol felt side effect less

No difference

Risks and Warnings for Delzicol (mesalamine)

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    • Higher risk if:
    • Preexisting kidney problems
    • Taking medications toxic to the kidney

    Delzicol (mesalamine) can cause kidney problems. Let you doctor know if you are unable to pass urine, notice a change in how much urine is passed, blood in the urine, or increased weight gain. Your doctor will likely check your kidney function before starting Delzicol (mesalamine) and periodically throughout treatment with this medication.

Common concerns from people taking Delzicol (mesalamine)

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Food
  • Take capsules with or without food three times daily if you're an adult, and twice daily for children.
Kidneys and liver
  • Delzicol (mesalamine) can cause kidney problems. Let you doctor know if you are unable to pass urine, notice a change in how much urine is passed, blood in the urine, or increased weight gain. Your doctor will likely check your kidney function before starting Delzicol (mesalamine) and periodically throughout treatment with this medication.