Metrogel

(metronidazole)

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Treats vaginal infections and acne rosacea.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Metrogel (metronidazole) is effective for bacterial infections or skin conditions, but you may need to avoid alcohol while using this.

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Quick facts about Metrogel
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (metronidazole)

Upsides

  • Works well for acne rosacea and most types of vaginal infections. It has fewer side-effects than oral tablets.
  • It is available as a generic product.
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What to expect from Metrogel, on one page

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Downsides

  • May cause skin irritation.
  • Drinking alcohol while taking Metrogel (metronidazole) can cause intense flushing of skin and nausea. It is less likely with the gel and cream formulations than oral tablets, but be aware.
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How it works

Metrogel (metronidazole) is a nitroimidazole antibiotic and antiprotozoal. It kills bacteria and reduces inflammation in patients with acne rosacea.

Quick facts about Metrogel
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (metronidazole)

Used for

Dosage forms

  • Cream, Gel, or Ointment
  • Vaginal Cream, Gel, or Ointment
Tried Metrogel? Write a review!

Prices and coupons

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What to expect when you take Metrogel (metronidazole) for Rosacea

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Skin irritation
  • Dry skin
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Side effect rates for Metrogel (metronidazole)

  • Vaginal discharge
    12%12%
  • Yeast infection
    10%10%
  • Genital irritation
    9%9%
  • Gastrointestinal discomfort
    7%7%
  • Headache
    5%5%
  • Nausea/vomiting
    4%4%
  • Pelvic discomfort
    3%3%
  • Unusual taste
    2%2%
  • Dizziness
    2%2%
  • Change in white blood cells
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Metrogel.

Metrogel (metronidazole)
Placebo

People taking Metrogel felt side effect more

People taking Metrogel felt side effect less

No difference

Risks and Warnings for Metrogel (metronidazole)

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    • Higher risk if:
    • › Existing nerve problems

    People who have taken the oral or injectable forms of Metrogel (metronidazole) have reported nerve problems. The risk of this side effect should be low when you're using gel or cream formulation, but let your doctor know if you experience burning, prickling, or numbness of your hands and feet.

Common concerns from people taking Metrogel (metronidazole)

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Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Metrogel
BProbably safe
Alcohol
  • Drinking alcohol while using Metrogel (metronidazole) may lead to bad reactions.
  • Drinking alcohol while taking Metrogel (metronidazole) can cause intense flushing of skin and nausea. It is less likely with the gel and cream formulations than oral tablets, but be aware.
  • Not worth it
    Didn’t work
    Big hassle
    Reviewed Metrogelon 8/25/2017It cost a fortune. I fainted three times after I had 2 drinks because I was never warned about alcohol use. I really got hurt.
    60
    Woman
    A few months
    Bacterial vaginosis