Mexitil

(mexiletine)

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Treats heart rate problems.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Mexitil (mexiletine) is a drug that helps the heart in extreme situations when it isn't beating normally, especially when other drugs haven't worked well.

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    $62.35
Quick facts about mexiletine
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (mexiletine)

Upsides

  • It's a decent option for treating life-threatening heart rate problems, especially when other medicines or procedures haven't worked.
  • It's available as a generic drug, so it should be more affordable than the brand version.
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What to expect from mexiletine, on one page

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Downsides

  • Your heart requires close monitoring while taking Mexitil (mexiletine) to make sure it is working well.
  • Mexitil (mexiletine) can cause some liver damage.
  • You'll need to be monitored regularly for side effects by taking routine blood tests and heart tests.
  • It's not a good choice if you have liver problems or a history of heart failure.
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What to expect from mexiletine, on one page

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How it works

Mexitil (mexiletine) is anti-arrhythmic medicine. It treats heart rate problems by blocking bad electrical signals in your heart and helps it keep beating normally.

Quick facts about mexiletine
  • Drug class: Cardiovascular
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (mexiletine)

Used for

  • Arrhythmia
  • Cardiac dysrhythmia - Congenital heart disease

Dosage forms

  • Pill
Tried mexiletine? Write a review!

Prices and coupons

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What to expect when you take Mexitil (mexiletine) for Anti-arrhythmic

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Vomiting
  • Dizziness
  • Nervousness
  • Tremor
  • Palpitations
  • Liver problems
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Side effect rates for Mexitil (mexiletine)

From 102 clinical trials of mexiletine when taken for anti-arrhythmia
  • Chest Pain
    80%80%
    4%4%
  • Nausea/Vomiting/Heartburn
    40%40%
    6%6%
  • Dizziness/Lightheadedness
    26%26%
    14%14%
  • Tremor
    13%13%
  • Nervousness
    11%11%
    6%6%
  • Coordination difficulties
    10%10%
  • Palpitations
    8%8%
    10%10%
  • Changes in sleep habits
    8%8%
    16%16%
  • Headache
    8%8%
    6%6%
  • Blurred Vision
    8%8%
    2%2%
  • Changes in sleep habits
    7%7%
  • Shortness of breath
    6%6%
    10%10%
  • Vision changes
    6%6%
  • Headache
    6%6%
  • Diarrhea
    5%5%
  • Weakness
    5%5%
  • Nervousness
    5%5%
  • Numbness
    4%4%
    2%2%
  • Rash
    4%4%
    2%2%
  • Fluid retention
    4%4%
  • Palpitations
    4%4%
  • Constipation
    4%4%
  • Fatigue
    4%4%
  • Rash
    4%4%
  • Chest pain
    3%3%
  • Appetite changes
    3%3%
  • Speech difficulties
    3%3%
  • Confusion
    3%3%
  • Shortness of breath
    3%3%
  • Dry mouth
    3%3%
  • Increased ventricular arrhythmias
    2%2%
  • Weakness
    2%2%
    4%4%
  • Fatigue
    2%2%
    2%2%
  • Tinnitus
    2%2%
    4%4%
  • Confusion
    2%2%
    2%2%
  • Numbness or tingling
    2%2%
  • Depression
    2%2%
  • Joint pain
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of mexiletine.

Mexitil (mexiletine)
Placebo

People taking mexiletine felt side effect more

People taking mexiletine felt side effect less

No difference

Risks and Warnings for Mexitil (mexiletine)

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    • Higher risk if:
    • Had a heart attack in the past 2 years

    Mexitil (mexiletine) can lead to an increased risk of death in patients who've had a heart attack. Mexitil (mexiletine) should only be used when no other options are available.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Pharmacist Q&A

Mexitil (mexiletine) questions for

Frequently Asked Questions

This medication treats life-threatening ventricular arrhythmias.

Who is this drug for?

This medication treats life-threatening ventricular arrhythmias.

Common concerns from people taking Mexitil (mexiletine)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for mexiletine
CWeigh risks vs. benefits
Food
  • Mexitil (mexiletine) can be taken with food.
Kidneys and liver
  • It's not a good choice if you have liver problems or a history of heart failure.