Diabeta

(glyburide)

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3.3/ 5 average rating with 110 reviewsforglyburide
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Lowers blood sugar.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

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Quick facts about glyburide
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (glyburide)

Upsides

  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
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What to expect from glyburide, on one page

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People’s experience with glyburide

110reviews so far. What do you think?

Downsides

  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Get our free fact sheet

What to expect from glyburide, on one page

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How it works

Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.

Quick facts about glyburide
  • Drug class: Endocrine
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (glyburide)

Used for

Dosage forms

  • Pill
People’s experience with glyburide

110reviews so far. What do you think?

Prices and coupons

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What to expect when you take Diabeta (glyburide) for Improves blood sugar levels

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Bloating/fullness
  • Heartburn
  • Allergic skin reactions
  • Blood problems
  • Blurred vision
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Side effect rates for Diabeta (glyburide)

  • Nausea and heartburn
    2%2%
  • Skin allergies
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of glyburide.

Diabeta (glyburide)
Placebo

People taking glyburide felt side effect more

People taking glyburide felt side effect less

No difference

Risks and Warnings for Diabeta (glyburide)

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    • Higher risk if:
    • › Over age 65
    • › Kidney problems
    • › Use of other blood sugar lowering medicines
    • › Alcohol
    • › Intense physical activity

    Diabeta (glyburide) can cause low blood sugar which can be life-threatening. This is more likely if you are elderly or have kidney problems. Talk to your doctor or pharmacist about the symptoms of low blood sugar and how to treat it.

Common concerns from people taking Diabeta (glyburide)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insertSee pregnancy safe medications
Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for glyburide
CWeigh risks vs. benefits
Alcohol
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Food
  • Eat well-balanced meals to avoid low blood sugar.
Kidneys and liver
  • Not ideal for elderly or those with poor kidney function.
Weight
  • Can cause weight gain, dizziness, or stomach upset.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not sure
    Worked well
    Some hassle
    Reviewed glyburideon 2/20/2018wish I'd known about weight gain
    67
    Woman
    A few months
    Would rather not say