Mifeprex

(mifepristone)

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Terminates early pregnancy.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Mifeprex (mifepristone) is a single pill for medical termination of pregnancy, but it can only be used for pregnancies that are less than 10 weeks along.

Quick facts about Mifeprex
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Mifeprex (mifepristone) is the first FDA-approved early option (10 weeks or less) pill for non-surgical abortion.
  • Mifeprex (mifepristone) and misoprostol are pills taken by mouth that may allow you to avoid anesthesia or surgery.
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What to expect from Mifeprex, on one page

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Downsides

  • Mifeprex (mifepristone) isn't approved for ending pregnancies that are further along than 10 weeks.
  • About 2 to 7 out of 100 women taking Mifeprex (mifepristone) will require a surgical procedure because the pregnancy didn't completely pass from the uterus during the termination procedurel.
  • If you are using an IUD (intrauterine device), it must be taken out before you take Mifeprex (mifepristone).
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Get our free fact sheet

What to expect from Mifeprex, on one page

Download Fact Sheet
How it works

Mifeprex (mifepristone) works by blocking progesterone, a naturally produced hormone that prepares the lining of the uterus for a fertilized egg to help maintain pregnancy.

Quick facts about Mifeprex
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Termination of pregnancy

Dosage forms

  • Pill
Tried Mifeprex? Write a review!

Prices and coupons

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What to expect when you take Mifeprex (mifepristone) for Termination of pregnancy

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Nausea
  • Weakness
  • Fever/chills
  • Vomiting
  • Diarrhea
  • Dizziness
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Side effect rates for Mifeprex (mifepristone)

From 1248 clinical trials of Mifeprex when taken for termination of pregnancy
  • Nausea
    63%63%
  • Weakness
    56%56%
  • Fever/chills
    48%48%
  • Vomiting
    43%43%
  • Headache
    43%43%
  • Dizziness
    40%40%
  • Diarrhea
    31%31%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Mifeprex.

Mifeprex (mifepristone)
Placebo

People taking Mifeprex felt side effect more

People taking Mifeprex felt side effect less

No difference

Risks and Warnings for Mifeprex (mifepristone)

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  • Mifeprex (mifepristone) can cause serious bacterial infections. Symptoms may also not be as obvious. If you have a fever that last longer than 4 hours, severe stomach pain, tenderness in your pelvis, rapid heartbeat, or if you have nausea, vomiting, diarrhea, or weakness more than 24 hours after taking Mifeprex (mifepristone), seek emergency care.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect