Minivelle

(estradiol patch)

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4.2/ 5 average rating with 17 reviewsforMinivelle
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Relieves menopause symptoms.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

The Minivelle (estradiol patch) is the mini-me of estrogen patches. It's used twice a week, available in five strengths, and has the least amount of skin irritation.

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    $87.71
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    $33.55
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Quick facts about Minivelle
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Minivelle (estradiol patch) is the smallest estrogen patch available. It's the size a dime and comes in 5 different strengths.
  • Causes little or no skin irritation and doesn't leave much adhesive on your skin.
  • Minivelle (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
  • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
  • Lowers your risk of fractures by keeping your bones healthy.
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What to expect from Minivelle, on one page

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People’s experience with Minivelle

17reviews so far. What do you think?

Downsides

  • You need to replace Minivelle (estradiol patch) twice a week, compared to other patches that are once a week.
  • Patches can fall off.
  • Increases your risk of uterine and breast cancer.
  • Increases your risk of developing blood clots and stroke.
  • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
  • Can't be used in people with liver problems.
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What to expect from Minivelle, on one page

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How it works

Minivelle (estradiol patch) replaces an estrogen hormone that your body loses during and after menopause. Higher levels of the hormone relieve symptoms of low estrogen, menopause, and prevent bone loss.

Quick facts about Minivelle
  • Drug class: Women's health
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Hot flashes
  • Prevention of bone thinning in postmenopausal women

Dosage forms

  • Patch
People’s experience with Minivelle

17reviews so far. What do you think?

Prices and coupons

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What to expect when you take Minivelle (estradiol patch) for Postmenopausal estrogen replacement

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Sinus infection
  • Back pain
  • Breast pain
  • Menstrual bleeding
  • Nausea
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Side effect rates for Minivelle (estradiol patch)

From 289 clinical trials of Minivelle when taken for postmenopausal estrogen replacement (0.1 mg/day)
  • Headache
    26%26%
    24%24%
  • Breast pain
    13%13%
  • Back pain
    11%11%
    6%6%
  • Menstrual bleeding
    11%11%
    5%5%
  • Influenza
    8%8%
    9%9%
  • Common cold
    8%8%
    15%15%
  • Nausea
    5%5%
    3%3%
  • Pain
    5%5%
    5%5%
  • Sinus infection
    5%5%
    10%10%
  • Lung infection
    5%5%
    6%6%
  • Neck pain
    5%5%
    1%1%
  • Limb pain
    5%5%
    6%6%
  • Sinus congestion
    5%5%
    5%5%
  • Joint pain
    4%4%
    6%6%
  • Depression
    3%3%
    4%4%
  • Constipation
    2%2%
    3%3%
  • Flu-like symptoms
    2%2%
    6%6%
  • Sinus headache
    2%2%
    5%5%
  • Anxiety
    2%2%
    3%3%
  • Trouble sleeping
    2%2%
    6%6%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Minivelle.

Minivelle (estradiol patch)
Placebo

People taking Minivelle felt side effect more

People taking Minivelle felt side effect less

No difference

Risks and Warnings for Minivelle (estradiol patch)

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    • Higher risk if:
    • › Using estrogen for more than one year

    Vaginal bleeding after menopause can be a warning sign of uterus (endometrial) cancer, so let your doctor know if you notice any unusual bleeding. Using medicines like Minivelle (estradiol patch) for more than a year can increase your risk. Talk to your doctor about other medicines you can take with Minivelle (estradiol patch) to protect yourself from cancer if you are worried.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Minivelle (estradiol patch)

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Alcohol
  • Worth it
    Worked well
    Low hassle
    Reviewed Minivelleon 3/10/2017Clean skin and then swab it with alcohol. Some patches are stickier than others; simetimes a whole box is drier than usual. Medical tape or a bandaid will keep it in place. Dry skin in winter is less sticky also. I put mine on firm not fatty areas. Get yout thyroid checked. Estrogen is a thyroid antagonist, so if you are on thyroid replacement, you will probably need to up your dose!
    57
    Woman
    Two years or more
    Hot flashes and night sweats
Weight
  • Can cause nausea, dizziness, bloating, and breast tenderness.