Provigil

(modafinil)

4.2/ 5 average rating with 28 reviewsforProvigil
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Improves alertness.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Provigil (modafinil) is effective in improving alertness, but it interacts with some medicines and shouldn't be used long-term.

Lowest price near you
  • Retail price
    $40.90
  • Savings
    11%
Quick facts about Provigil
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (modafinil)

Upsides

  • Provigil (modafinil) is a nonstimulant medication that improves alertness.
  • Provigil (modafinil) is available in a cheaper, generic version.
  • Provigil (modafinil) is good at decreasing excessive sleepiness in shift work sleep disorder.
  • If you need to sleep in the daytime, this medication won't effect you.
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What to expect from Provigil, on one page

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People’s experience with Provigil

28reviews so far. What do you think?

Downsides

  • Provigil (modafinil) can be habit forming, so it shouldn't be used for long-term treatment.
  • Provigil (modafinil) is not a good choice if you have liver problems.
  • May not be a good option if you are taking hormonal contraception like birth control pills.
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What to expect from Provigil, on one page

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How it works

Provigil (modafinil) is a stimulant that helps you feel awake. Researchers don't know exactly how Provigil (modafinil) works, but it likely effects chemicals (neurotransmitters) in the brain to increase alertness.

Quick facts about Provigil
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (modafinil)

Dosage forms

  • Pill
People’s experience with Provigil

28reviews so far. What do you think?

Prices and coupons

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What to expect when you take Provigil (modafinil) for Narcolepsy

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Headache
  • Nausea
  • Stuffy nose
  • Nervousness
  • Diarrhea
  • Loss of appetite
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Side effect rates for Provigil (modafinil)

From 1501 clinical trials of Provigil when taken for narcolepsy, obstructive sleep apnea (osa), or shift work disorder (swd).
  • Headache
    34%34%
    23%23%
  • Nausea
    11%11%
    3%3%
  • Nervousness
    7%7%
    3%3%
  • Stuffy nose
    7%7%
    6%6%
  • Back pain
    6%6%
    5%5%
  • Diarrhea
    6%6%
    5%5%
  • Indigestion
    5%5%
    4%4%
  • Difficulty sleeping
    5%5%
    1%1%
  • Anxiety
    5%5%
    1%1%
  • Dizziness
    5%5%
    4%4%
  • Flu symptoms
    4%4%
    3%3%
  • Dry mouth
    4%4%
    2%2%
  • Loss of appetite
    4%4%
    1%1%
  • Throat inflammation
    4%4%
    2%2%
  • Chest pain
    3%3%
    1%1%
  • High blood pressure
    3%3%
    1%1%
  • Fast heart beat
    2%2%
    1%1%
  • Palpitation
    2%2%
    1%1%
  • Dilation of blood vessels
    2%2%
  • Constipation
    2%2%
    1%1%
  • Abnormal liver function
    2%2%
    1%1%
  • Depression
    2%2%
    1%1%
  • Burning/tingling sensation
    2%2%
  • Drowsiness
    2%2%
    1%1%
  • Lung disorder
    2%2%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Provigil.

Provigil (modafinil)
Placebo

People taking Provigil felt side effect more

People taking Provigil felt side effect less

No difference

Risks and Warnings for Provigil (modafinil)

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    • Higher risk if:
    • Allergy to Provigil (modafinil)

    In some people, Provigil (modafinil) can cause serious allergic reactions and life-threatening organ failure. Report any skin rash, fever, swelling, or trouble breathing to a doctor immediately. Severe and fatal skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) can occur anytime, and as early as the first day you take Provigil (modafinil). Tell your doctor or get medical help right away if you notice sores or fluid-filled blisters on your skin, lips, or inside your mouth. If you have this reaction you won't be able to continue taking this medication.

Pharmacist Q&A

Provigil (modafinil) questions for

Frequently Asked Questions

This medication reduces excessive sleepiness associated with narcolepsy.

Who is this drug for?

This medication reduces excessive sleepiness associated with narcolepsy.

Common concerns from people taking Provigil (modafinil)

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Interactions
  • Provigil (modafinil) has many drug interactions and can lower the strength of your birth control pill, so use an additional form of birth control while using Provigil (modafinil).
Alcohol
  • Don't drink alcohol while taking Provigil (modafinil).
Kidneys and liver
  • Provigil (modafinil) is processed by the kidney and liver. If you have kidney or liver problems, you may need to take a lower dose to prevent side effects.
Sleep
  • If you need to sleep in the daytime, this medication won't effect you.
  • Worth it
    Low hassle
    Reviewed Provigilon 7/22/2016I have RLS, and helped me tremendously with sleepiness in the daytime. As long as I did not take after noon, had no problems sleeping. It is expensive and my inurance company just stopped paying for it. Just started ritalin today. Wish lu
    59
    Woman
    Excessive daytime sleepiness