Northera

(droxidopa)

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Maintains your blood pressure.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Northera (droxidopa) is the only medicine available to keep your blood pressure normal if you have Parkinson's disease. However, you have to see your doctor regularly, and it can be very expensive.

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  • Lowest price with coupon
    $2352.58
Quick facts about Northera
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Northera (droxidopa) has been shown to keep your blood pressure normal if you have Parkinson's disease.
  • Compared to other blood pressure medicines, the side effects of Northera (droxidopa) are much milder.
  • There are programs available that can make Northera (droxidopa) more affordable if your insurance copay is too high.
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What to expect from Northera, on one page

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Downsides

  • You have to see your doctor regularly while taking Northera (droxidopa).
  • Northera (droxidopa) is only available as a brand name, so your copay might be expensive.
  • You have to sleep with your upper body elevated to make sure your blood pressure doesn't get too high.
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What to expect from Northera, on one page

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How it works

Northera (droxidopa) is droxidopa, which turns into norepinephrine in your body. Norepinephrine stops your blood pressure from getting too low by tightening your blood vessels when you get up.

Quick facts about Northera
  • Drug class: Neuro/psych
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Used for

  • Dizziness and lightheadedness in Parkinson's disease and other conditions
  • Dopamine beta-hydroxylase deficiency
  • Non-diabetic autonomic neuropathy

Dosage forms

  • Pill
Tried Northera? Write a review!

Prices and coupons

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What to expect when you take Northera (droxidopa) for Neurogenic orthostatic hypotension

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  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
    First few daysDays
    First few weeksWeeks
    First few monthsMonths
  • Possible side effects
  • Worsening heart disease
  • Headache
  • Dizziness
  • Nausea
  • High blood pressure
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Side effect rates for Northera (droxidopa)

From 222 clinical trials of Northera when taken for neurogenic orthostatic hypotension
  • Falls
    24%24%
  • Urinary tract infections
    15%15%
  • Headache
    13%13%
    7%7%
  • Fainting
    13%13%
  • Dizziness
    10%10%
    5%5%
  • Nausea
    9%9%
    5%5%
  • High blood pressure
    7%7%
    1%1%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Northera.

Northera (droxidopa)
Placebo

People taking Northera felt side effect more

People taking Northera felt side effect less

No difference

Risks and Warnings for Northera (droxidopa)

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  • Your blood pressure can get very high while taking Northera (droxidopa), especially while lying down. You should measure your blood pressure more frequently when you're first starting it or changing doses. You should also sleep with your upper body elevated.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Northera (droxidopa)

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Sleep
  • You have to sleep with your upper body elevated to make sure your blood pressure doesn't get too high.