Pamelor

(nortriptyline)

4.0/ 5 average rating with 19 reviewsforPamelor
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Improves mood.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Pamelor (nortriptyline) is a good option for treating depression, especially for people who also have problems with persistent nerve pain, but may take 6 to 8 weeks to feel the full effects on your mood.

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Quick facts about Pamelor
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (nortriptyline)

Upsides

  • Helpful with treating certain types of pain, like migraines or nerve-related pain.
  • Generally well tolerated and has fewer side effects than other medicines in the same class of drugs.
  • Available as a generic in 2 different forms: capsule and liquid.
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What to expect from Pamelor, on one page

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People’s experience with Pamelor

19reviews so far. What do you think?

Downsides

  • Side effects are usually manageable, but can be annoying.
  • There's an increased chance of it causing heart problems, especially in people with a history of heart problems.
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How it works

Pamelor (nortriptyline) is a tricyclic antidepressant (TCA). It helps improve your mood by adjusting the levels of serotonin, norepinephrine, and other similar neurotransmitters in your brain.

Quick facts about Pamelor
  • Drug class: Mental health
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (nortriptyline)

Used for

Dosage forms

  • Pill
  • Liquid
People’s experience with Pamelor

19reviews so far. What do you think?

Prices and coupons

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What to expect when you take Pamelor (nortriptyline) for Depression

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  • First few daysDays
    First few weeksWeeks
    First few monthsMonths
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few daysDays
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  • Possible side effects
  • Constipation
  • Blurred vision
  • Difficulty urinating
  • Low blood pressure
  • Dry mouth
  • Anxiety
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Side effect rates for Pamelor (nortriptyline)

Risks and Warnings for Pamelor (nortriptyline)

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    • Higher risk if:
    • Age 24 years or younger
    • Changing the dose

    Pamelor (nortriptyline) may increase the risk of suicidal thoughts or behavior. Watch for worsening depression or any unusual changes in mood or behavior, especially during the first few months of treatment or when the dose changes. Report anything concerning to a doctor right away. Pamelor (nortriptyline) is not approved for use in children.

    This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Pamelor (nortriptyline)

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Alcohol
  • Avoid drinking alcohol while taking this medication.
  • Worth it
    Low hassle
    Reviewed Pameloron 8/28/2017Take at night, give it time. Don't drink with alcohol.
    27
    Woman
    A few months
Food
  • Take it with food and/or at bedtime to decrease the potential side effects.
Pain
  • Not sure
    Low hassle
    Reviewed Pameloron 8/21/2017It is a nerve blocker for nerve pain. I suppose so, I don't know if it works or not. I take one at night before bed and if it works I don't know cause I am still the same me in the morning. I don't feel any differently than usual. Although I also take gabapentin for nerve pain.
    64
    Woman
    A few months
    Depression