Odefsey

(emtricitabine / rilpivirine / tenofovir)

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Treats HIV infection

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Our bottom line

Odefsey (emtricitabine / rilpivirine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections. It's similar to Complera, but contains a newer HIV drug which has shown to cause less harmful effects on your kidneys and bones.

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  • Lowest price with coupon
    $2670.55
Quick facts about Odefsey
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Upsides

  • Odefsey (emtricitabine / rilpivirine / tenofovir) combines three medications into one tablet, so it's easy to take.
  • Odefsey (emtricitabine / rilpivirine / tenofovir) is currently the smallest combination HIV tablet available.
  • Odefsey (emtricitabine / rilpivirine / tenofovir) works similar to Complera, but is less likely to cause harmful side effects on your kidneys and bones.
  • Odefsey (emtricitabine / rilpivirine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
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What to expect from Odefsey, on one page

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Downsides

  • Odefsey (emtricitabine / rilpivirine / tenofovir) has to be taken with a light meal.
  • Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need an acid reducer, try taking an antacid like calcium carbonate either 2 hours before or 4 hours after Odefsey (emtricitabine / rilpivirine / tenofovir). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Odefsey (emtricitabine / rilpivirine / tenofovir).
  • Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
  • Can cause abnormal heart rhythm.
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What to expect from Odefsey, on one page

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How it works

Odefsey (emtricitabine / rilpivirine / tenofovir) is a combination pill that contains three antiretroviral (ARV) drugs. It treats HIV infections by preventing the virus from attacking your immune cells and multiplying.

Quick facts about Odefsey
  • Drug class: Infection
  • Rx status: Prescription only
  • Generic status: No lower cost generic available

Dosage forms

  • Pill
Tried Odefsey? Write a review!

Prices and coupons

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What to expect when you take Odefsey (emtricitabine / rilpivirine / tenofovir) for HIV treatment

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  • First few hoursHours
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  • Effectiveness
  • Starts to kick in
    Full effects
  • First few hoursHours
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  • Possible side effects
  • Nausea
  • Headache
  • Depressive disorders
  • Insomnia
  • Rash
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Side effect rates for Odefsey (emtricitabine / rilpivirine / tenofovir)

From 886 clinical trials of Odefsey when taken for hiv infection
  • Headache
    19%19%
  • Depression
    19%19%
  • Somnolence
    14%14%
  • Nausea
    11%11%
  • Dizziness
    8%8%
  • Abdominal pain
    8%8%
  • Vomiting
    6%6%
  • Rash
    6%6%
0%
10%
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30%
40%
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70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Odefsey.

Odefsey (emtricitabine / rilpivirine / tenofovir)
Placebo

People taking Odefsey felt side effect more

People taking Odefsey felt side effect less

No difference

Risks and Warnings for Odefsey (emtricitabine / rilpivirine / tenofovir)

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    • Higher risk if:
    • Liver disease
    • Women
    • Obesity

    Odefsey (emtricitabine / rilpivirine / tenofovir) can cause this rare but life-threatening condition. Symptoms include difficulty breathing, nausea, vomiting, right sided stomach pain, and dark urine . This is a medical emergency and you should get help right away.

Means that some groups have a high risk of experiencing this side effect

Common concerns from people taking Odefsey (emtricitabine / rilpivirine / tenofovir)

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Food
  • Take each dose with a light meal.