Opana
(oxymorphone)
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Treats pain.
Skip Upsides & Downsides section. Skip to side effects section.
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Our bottom line
Opana (oxymorphone) treats severe pain, but prolonged use can lead to dependence, tolerance, and possibly addiction.
Quick facts about Opana
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (oxymorphone)
Upsides
- Generic is available, making Opana (oxymorphone) an affordable option.
- Available in both short-acting and long-acting formulations.
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What to expect from Opana, on one page
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Downsides
- Opana (oxymorphone) is a powerful pain reliever, which can be dangerous at high doses or when taken for a long time.
- Opana (oxymorphone) needs to be taken on an empty stomach, which may be inconvenient.
- People with kidney or liver problems need to use extra caution with Opana (oxymorphone), since these conditions increases the likelihood of an overdose.
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What to expect from Opana, on one page
Download Fact SheetHow it works
Opana (oxymorphone) is an opioid that works on the brain to reduce your perception of pain.
Quick facts about Opana
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (oxymorphone)
Used for
- Pain
- Severe, chronic pain
Dosage forms
- Pill
- Extended-release pill
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Prices and coupons
Skip prices section. Skip to what to expect section.Prices and coupons for 30 (20mg) tablets of oxymorphone near
Pay as low as$274.07Retail priceRetail priceLearn more- CostcoGet free coupon$271.11
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See more prices and coupons in your areaWhat to expect when you take Opana (oxymorphone) for Pain
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Full effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Physical dependence
- Constipation
- Sleepiness
- Nausea
- Dizziness
- Itching
Side effect rates for Opana (oxymorphone)
From 1720 clinical trials of Opana when taken for pain
- Nausea33%33%13%13%
- Constipation28%28%13%13%
- Dizziness18%18%8%8%
- Sleepiness17%17%2%2%
- Vomiting16%16%4%4%
- Itching15%15%8%8%
- Headache12%12%6%6%
- Increased sweating9%9%9%9%
- Dry mouth6%6%
- Sedation6%6%8%8%
- Diarrhea4%4%6%6%
- Difficulty sleeping4%4%2%2%
- Fatigue4%4%1%1%
- Decreased appetite3%3%
- Stomach pain3%3%2%2%
0%
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Where we got our data »
The placebo bar shows how common a side effect was for people taking a sugar pill instead of Opana.
Opana (oxymorphone)
Placebo
People taking Opana felt side effect more
People taking Opana felt side effect less
No difference
Risks and Warnings for Opana (oxymorphone)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Taking more than the prescribed dose
- › Long-term use
- › History of drug abuse
- › Younger age
If taken regularly for a long time, Opana (oxymorphone) can cause physical dependence and tolerance. This means that you may need larger doses to achieve the same pain relief, and experience withdrawal symptoms if the medicine is suddenly stopped. Do not take more than what is prescribed and talk to your doctor about alternatives if this is a concern.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Means that some groups have a high risk of experiencing this side effect
Common concerns from people taking Opana (oxymorphone)
Final section. Do you want to return to drug navigation?Kidneys and liver
- People with kidney or liver problems need to use extra caution with Opana (oxymorphone), since these conditions increases the likelihood of an overdose.
Pain
- Worth itLow hassleReviewed oxymorphoneon 11/23/2020I have been on every pain medecine under the sun. And the o ky thing that works around the clock is opana or generic oxymorphone!I have a pimched ciatic nerve and my L5 and right shoulder is really messed up. Only meds that work are the opana instant release.37ManTwo years or moreSevere, chronic pain
- Worth itSome hassleReviewed Opanaon 9/1/2017Yes; over the years I've tried everything for my chronic pain and found it to work better than any other medication. It's just a shame people abuse it and make it look bad for everyone!!!63ManTwo years or moreChronic (Severe)
Sleep
- Mixing alcohol and Opana (oxymorphone) can result in excessive drowsiness and potentially fatal overdose. Avoid alcoholic beverages while taking Opana (oxymorphone).