Opana
(oxymorphone)
Treats pain.
Our bottom line
Opana (oxymorphone) treats severe pain, but prolonged use can lead to dependence, tolerance, and possibly addiction.
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (oxymorphone)
Upsides
- Generic is available, making Opana (oxymorphone) an affordable option.
- Available in both short-acting and long-acting formulations.
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What to expect from Opana, on one page
Download Fact SheetDownsides
- Opana (oxymorphone) is a powerful pain reliever, which can be dangerous at high doses or when taken for a long time.
- Opana (oxymorphone) needs to be taken on an empty stomach, which may be inconvenient.
- People with kidney or liver problems need to use extra caution with Opana (oxymorphone), since these conditions increases the likelihood of an overdose.
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What to expect from Opana, on one page
Download Fact SheetOpana (oxymorphone) is an opioid that works on the brain to reduce your perception of pain.
- Drug class: Pain
- Rx status: Prescription only
- Generic status: Lower-cost generic available (oxymorphone)
Used for
- Pain
- Severe, chronic pain
Dosage forms
- Pill
- Extended-release pill
Prices and coupons
Skip prices section. Skip to what to expect section.- Kroger PharmacyGet free coupon$157.53
- Medicine ShoppeGet free coupon$157.53
What to expect when you take Opana (oxymorphone) for Pain
Skip what to expect section. Skip to side effects section.- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Effectiveness
- Full effects
- First few hoursHoursFirst few daysDaysFirst few weeksWeeksFirst few monthsMonths
- Possible side effects
- Physical dependence
- Constipation
- Sleepiness
- Nausea
- Dizziness
- Itching
Side effect rates for Opana (oxymorphone)
- Nausea33%33%13%13%
- Constipation28%28%13%13%
- Dizziness18%18%8%8%
- Sleepiness17%17%2%2%
- Vomiting16%16%4%4%
- Itching15%15%8%8%
- Headache12%12%6%6%
- Increased sweating9%9%9%9%
- Dry mouth6%6%
- Sedation6%6%8%8%
- Diarrhea4%4%6%6%
- Difficulty sleeping4%4%2%2%
- Fatigue4%4%1%1%
- Decreased appetite3%3%
- Stomach pain3%3%2%2%
The placebo bar shows how common a side effect was for people taking a sugar pill instead of Opana.
People taking Opana felt side effect more
People taking Opana felt side effect less
Risks and Warnings for Opana (oxymorphone)
Skip risks section. Skip to common concerns section.- Higher risk if:
- › Taking more than the prescribed dose
- › Long-term use
- › History of drug abuse
- › Younger age
If taken regularly for a long time, Opana (oxymorphone) can cause physical dependence and tolerance. This means that you may need larger doses to achieve the same pain relief, and experience withdrawal symptoms if the medicine is suddenly stopped. Do not take more than what is prescribed and talk to your doctor about alternatives if this is a concern.
This is a black box warning. The FDA requires this warning when there is a significant risk of serious or life-threatening effects that anyone taking the drug should consider.
Common concerns from people taking Opana (oxymorphone)
Final section. Do you want to return to drug navigation?- People with kidney or liver problems need to use extra caution with Opana (oxymorphone), since these conditions increases the likelihood of an overdose.
- Worth itSome hassleReviewed Opanaon 9/1/2017Yes; over the years I've tried everything for my chronic pain and found it to work better than any other medication. It's just a shame people abuse it and make it look bad for everyone!!!63ManTwo years or moreChronic (Severe)
- Mixing alcohol and Opana (oxymorphone) can result in excessive drowsiness and potentially fatal overdose. Avoid alcoholic beverages while taking Opana (oxymorphone).