Trileptal

(Oxcarbazepine)

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Prevents seizures.

Skip Upsides & Downsides section. Skip to side effects section.

Our bottom line

Trileptal (Oxcarbazepine) is effective at preventing seizures and you don’t need to get regular blood tests to make sure it’s effective, but it has many drug interactions.

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Quick facts about Trileptal
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (oxcarbazepine)

Upsides

  • Trileptal (Oxcarbazepine) is effective at lowering the frequency of seizures, especially for people with partial seizures.
  • If you have trouble swallowing tablets, Trileptal (Oxcarbazepine) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
  • Available in a generic form.
Tried Trileptal? Write a review!

Downsides

  • It’s important to take your dose on time so that Trileptal (Oxcarbazepine) has steady levels in your body.
  • Interacts with many other medicines and supplements.
  • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Being pregnant lowers the levels of Trileptal (Oxcarbazepine), so the medicine might not be as effective at preventing seizures.
How it works

Trileptal (Oxcarbazepine) is an antiepileptic medication. It reduces seizures by blocking certain types of nerve activity that regulate how your brain cells communicate with each other.

Quick facts about Trileptal
  • Drug class: Neurology
  • Rx status: Prescription only
  • Generic status: Lower-cost generic available (oxcarbazepine)

Dosage forms

  • Pill
  • Liquid
Tried Trileptal? Write a review!

Prices and coupons

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Side effect rates for Trileptal (Oxcarbazepine)

From 104 clinical trials of Trileptal when taken for seizures
  • Dizziness
    22%22%
    6%6%
  • Nausea
    16%16%
    12%12%
  • Headache
    13%13%
    10%10%
  • Any adverse effect
    9%9%
  • Diarrhea
    7%7%
    2%2%
  • Vomiting
    7%7%
    6%6%
  • Upper Respiratory Tract Infection
    7%7%
  • Constipation
    5%5%
  • Dyspepsia
    5%5%
    4%4%
  • Ataxia
    5%5%
  • Nervousness
    5%5%
    2%2%
  • Falling Down NOS
    4%4%
  • Pain Back
    4%4%
    2%2%
  • Amnesia
    4%4%
    2%2%
  • Coordination Abnormal
    4%4%
    2%2%
  • Tremor
    4%4%
  • Epistaxis
    4%4%
  • Infection Chest
    4%4%
  • Sinusitis
    4%4%
    2%2%
  • Rash
    4%4%
    2%2%
  • Vision Abnormal
    4%4%
  • Dizziness
    2%2%
  • Nausea
    2%2%
  • Rash
    2%2%
0%
10%
20%
30%
40%
50%
60%
70%
80%
Where we got our data »

The placebo bar shows how common a side effect was for people taking a sugar pill instead of Trileptal.

Trileptal (Oxcarbazepine)
Placebo

People taking Trileptal felt side effect more

People taking Trileptal felt side effect less

No difference

Risks and Warnings for Trileptal (Oxcarbazepine)

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    • Higher risk if:
    • Age 65 or older
    • dehydration
    • Taking diuretics (water pills)

    Trileptal (Oxcarbazepine) may increase the risk of low sodium levels in the blood (hyponatremia). Watch out for symptoms including headache, difficulty concentrating, memory problems, confusion, weakness, and unsteadiness, which may lead to falls. Talk to a doctor right away before developing more serious symptoms, such as hallucination, fainting, coma, and death.

Pharmacist Q&A

Trileptal (Oxcarbazepine) questions for

Frequently Asked Questions

This medication treats partial seizures in adults.

Who is this drug for?

This medication treats partial seizures in adults.

Common concerns from people taking Trileptal (Oxcarbazepine)

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Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Tip: Always talk with your doctor before you take any medication while pregnant.
FDA pregnancy category for Trileptal
CWeigh risks vs. benefits
Interactions
  • Interacts with many other medicines and supplements.
  • Not worth it
    Big hassle
    Reviewed TrileptalMany drug interactions. Increased hypothyroidism and arthritis pain and made pain medication ineffective. Caused low sodium and other meds did not work. Did control seizures. Not worth it if you have multiple health issues.
    42
    Woman
    Two years or more
Food
  • Trileptal (Oxcarbazepine) can be taken with or without food.
Kidneys and liver
  • Hepatitis and liver failure have been reported with Trileptal (Oxcarbazepine). However, this is very rare. Call your doctor right away if you start to have clay-colored stools, yellowing of the eyes or skin, dark urine, stomach pain, or if you are eating less than usual without trying to.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
Sleep
  • Trileptal (Oxcarbazepine) may increase the risk of low sodium levels in the blood (hyponatremia). Watch out for symptoms including headache, difficulty concentrating, memory problems, confusion, weakness, and unsteadiness, which may lead to falls. Talk to a doctor right away before developing more serious symptoms, such as hallucination, fainting, coma, and death.
  • You can experience dizziness, drowsiness, double vision, stomach upset, and trouble with coordination while on this.
  • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
Weight
  • Not sure
    Low hassle
    Reviewed Trileptalon 6/22/2017I took it for emotional balance without weight gain. Its better than Depakote for me but I want something better.
    25
    Man
    A few months